PDB entry 5gds
View 5gds on RCSB PDB site
Description: hirunorms are true hirudin mimetics. the crystal structure of human alpha-thrombin:hirunorm v complex
Class: hydrolase/hydrolase inhibitor
Keywords: SERINE PROTEASE-INHIBITOR complex, THROMBIN, THROMBIN SYNTHETIC INHIBITORS, ANTITHROMBOTICS, HIRUNORMS, HIRUDIN-LIKE BINDING MODE, BLOOD COAGULATION, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on
1997-07-17, released
1998-01-21
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-07-29, with a file datestamp of
2020-07-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: alpha-thrombin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5gds.1 - Chain 'I':
Compound: hirunorm v
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: alpha-thrombin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5gds.1 - Heterogens: NAG, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence, based on SEQRES records: (download)
>5gdsH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>5gdsH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwgqpsvlqvvnlpiverpvckdstriritdnmf
cagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrl
kkwiqkvidqfge
- Chain 'I':
No sequence available.
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>5gdsL (L:)
tfgsgeadcglrplfekksledkterellesyidgr