PDB entry 5g0i

View 5g0i on RCSB PDB site
Description: Crystal structure of Danio rerio HDAC6 CD1 and CD2 (linker cleaved) in complex with Nexturastat A
Class: cell cycle
Keywords: cell cycle, histone, histone deacetylase
Deposited on 2016-03-18, released 2016-07-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-09-28, with a file datestamp of 2016-09-23.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hdac6
    Species: Danio rerio [TaxId:7955]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5g0ia1, d5g0ia2
  • Chain 'B':
    Compound: hdac6
    Species: Danio rerio [TaxId:7955]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5g0ib1, d5g0ib2
  • Heterogens: ZN, K, N4R, CL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5g0iA (A:)
gpknlqearrkgrmdrskaeeemsnelqnldvqgkskatgtglvyvdaftrfhclwdash
pecparvstvmemletegllgrcvqvearavtedelllvhtkeyvelmkstqnmteeelk
tlaekydsvylhpgffssaclsvgsvlqlvdkvmtsqlrngfsinrppghhaqadkmngf
cmfnnlaiaaryaqkrhrvqrvlivdwdvhhgqgiqyifeedpsvlyfsvhryedgsfwp
hlkesdsssvgsgagqgyninlpwnkvgmesgdyitafqqlllpvayefqpqlvlvaagf
davigdpkggmqvspecfsilthmlkgvaqgrlvlaleggynlqstaegvcasmrsllgd
pcphlpssgapcesalksisktisdlypfwkslqtfeggplsevsplpapvcaevkvssp
itglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelalc
hsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqvr
navaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqhi
feeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaaf
hhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliile
ggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslrvnip
eslrlslpspkpkgkctpggkgkksprqs

    Sequence, based on observed residues (ATOM records): (download) 
    >5g0iA (A:)
skatgtglvyvdaftrfhclwdashpecparvstvmemletegllgrcvqvearavtede
lllvhtkeyvelmkstqnmteeelktlaekydsvylhpgffssaclsvgsvlqlvdkvmt
sqlrngfsinrppghhaqadkmngfcmfnnlaiaaryaqkrhrvqrvlivdwdvhhgqgi
qyifeedpsvlyfsvhryedgsfwphlkesdsssvgsgagqgyninlpwnkvgmesgdyi
tafqqlllpvayefqpqlvlvaagfdavigdpkggmqvspecfsilthmlkgvaqgrlvl
aleggynlqstaegvcasmrsllgdpcphlpssgapcesalksisktisdlypfwkslqt
fepitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeel
alchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtg
qvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngt
qhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeym
aafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvli
ileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslrv
ni

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5g0iB (B:)
gpknlqearrkgrmdrskaeeemsnelqnldvqgkskatgtglvyvdaftrfhclwdash
pecparvstvmemletegllgrcvqvearavtedelllvhtkeyvelmkstqnmteeelk
tlaekydsvylhpgffssaclsvgsvlqlvdkvmtsqlrngfsinrppghhaqadkmngf
cmfnnlaiaaryaqkrhrvqrvlivdwdvhhgqgiqyifeedpsvlyfsvhryedgsfwp
hlkesdsssvgsgagqgyninlpwnkvgmesgdyitafqqlllpvayefqpqlvlvaagf
davigdpkggmqvspecfsilthmlkgvaqgrlvlaleggynlqstaegvcasmrsllgd
pcphlpssgapcesalksisktisdlypfwkslqtfeggplsevsplpapvcaevkvssp
itglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelalc
hsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqvr
navaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqhi
feeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaaf
hhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliile
ggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslrvnip
eslrlslpspkpkgkctpggkgkksprqs

    Sequence, based on observed residues (ATOM records): (download) 
    >5g0iB (B:)
katgtglvyvdaftrfhclwdashpecparvstvmemletegllgrcvqvearavtedel
llvhtkeyvelmkstqnmteeelktlaekydsvylhpgffssaclsvgsvlqlvdkvmts
qlrngfsinrppghhaqadkmngfcmfnnlaiaaryaqkrhrvqrvlivdwdvhhgqgiq
yifeedpsvlyfsvhryedgsfwphlkesdsssvgsgagqgyninlpwnkvgmesgdyit
afqqlllpvayefqpqlvlvaagfdavigdpkggmqvspecfsilthmlkgvaqgrlvla
leggynlqstaegvcasmrsllgdpcphlpssgapcesalksisktisdlypfwkslqtf
pitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelal
chsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqv
rnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqh
ifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaa
fhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliil
eggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslrvni