PDB entry 5fyt

View 5fyt on RCSB PDB site
Description: Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment (5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl)acetic acid (N09996a)
Class: oxidoreductase
Keywords: oxidoreductase, jarid1b, plu1, pandda, fragment soaking, x-ray fragment screening, structural genomics consortium, sgc
Deposited on 2016-03-09, released 2016-03-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.87 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific demethylase 5B
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UGL1
      • expression tag (0-1)
    Domains in SCOPe 2.08: d5fyta1, d5fyta2, d5fyta3
  • Heterogens: ZN, MN, WQS, EDO, DMS, PO4, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fytA (A:)
smflpppecpvfepsweefadpfafihkirpiaeqtgickvrpppdwqppfacdvdklhf
tpriqrlneleaqtrvklggggardytlrtfgemadafksdyfnmpvhmvptelvekefw
rlvstieedvtveygadiaskefgsgfpvrdgkiklspeeeeyldsgwnlnnmpvmeqsv
lahitadicgmklpwlyvgmcfssfcwhiedhwsysinylhwgepktwygvpgyaaeqle
nvmkklapelfvsqpdllhqlvtimnpntlmthevpvyrtnqcagefvitfprayhsgfn
qgfnfaeavnfctvdwlplgrqcvehyrllhrycvfshdemickmaskadvldvvvastv
qkdmaimiedekalretvrklgvidsermdfellpdderqcvkckttcfmsaiscsckpg
llvclhhvkelcscppykyklryrytlddlypmmnalklraesynewalnvnealeaki

    Sequence, based on observed residues (ATOM records): (download) 
    >5fytA (A:)
smflpppecpvfepsweefadpfafihkirpiaeqtgickvrpppdwqppfacdvdklhf
tpriqrlneleaqtrvklrdytlrtfgemadafksdyfnmpvhmvptelvekefwrlvst
ieedvtveygadiaskefgsgfpvrdiklspeeeeyldsgwnlnnmpvmeqsvlahitad
icgmklpwlyvgmcfssfcwhiedhwsysinylhwgepktwygvpgyaaeqlenvmkkla
pelfvsqpdllhqlvtimnpntlmthevpvyrtnqcagefvitfprayhsgfnqgfnfae
avnfctvdwlplgrqcvehyrllhrycvfshdemickmaskadvldvvvastvqkdmaim
iedekalretvrklgvidsermdfellpdderqcvkckttcfmsaiscsckpgllvclhh
vkelcscppykyklryrytlddlypmmnalklrae