PDB entry 5fys

View 5fys on RCSB PDB site
Description: Crystal structure of the catalytic domain of human JARID1B in complex with D-2-hydroxyglutarate
Class: oxidoreductase
Keywords: oxidoreductase, jarid1b, plu1, tca intermediate
Deposited on 2016-03-09, released 2017-03-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific demethylase 5B
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UGL1
      • expression tag (0-1)
    Domains in SCOPe 2.08: d5fysa1, d5fysa2, d5fysa3
  • Heterogens: ZN, MN, EPE, EDO, 2HG, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fysA (A:)
smflpppecpvfepsweefadpfafihkirpiaeqtgickvrpppdwqppfacdvdklhf
tpriqrlneleaqtrvklggggardytlrtfgemadafksdyfnmpvhmvptelvekefw
rlvstieedvtveygadiaskefgsgfpvrdgkiklspeeeeyldsgwnlnnmpvmeqsv
lahitadicgmklpwlyvgmcfssfcwhiedhwsysinylhwgepktwygvpgyaaeqle
nvmkklapelfvsqpdllhqlvtimnpntlmthevpvyrtnqcagefvitfprayhsgfn
qgfnfaeavnfctvdwlplgrqcvehyrllhrycvfshdemickmaskadvldvvvastv
qkdmaimiedekalretvrklgvidsermdfellpdderqcvkckttcfmsaiscsckpg
llvclhhvkelcscppykyklryrytlddlypmmnalklraesynewalnvnealeaki

    Sequence, based on observed residues (ATOM records): (download) 
    >5fysA (A:)
smflpppecpvfepsweefadpfafihkirpiaeqtgickvrpppdwqppfacdvdklhf
tpriqrlneleaqtrvkdytlrtfgemadafksdyfnmpvhmvptelvekefwrlvstie
edvtveygadiaskefgsgfpvrdiklspeeeeyldsgwnlnnmpvmeqsvlahitadic
gmklpwlyvgmcfssfcwhiedhwsysinylhwgepktwygvpgyaaeqlenvmkklape
lfvsqpdllhqlvtimnpntlmthevpvyrtnqcagefvitfprayhsgfnqgfnfaeav
nfctvdwlplgrqcvehyrllhrycvfshdemickmaskadvldvvvastvqkdmaimie
dekalretvrklgvidsermdfellpdderqcvkckttcfmsaiscsckpgllvclhhvk
elcscppykyklryrytlddlypmmnalklrae