PDB entry 5fw6

View 5fw6 on RCSB PDB site
Description: Structure of human transthyretin mutant A108V
Class: transport protein
Keywords: transport protein, trasnport protein, t4-binding, t4-binding protein non-amyloidogenic
Deposited on 2016-02-12, released 2017-03-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-06-14, with a file datestamp of 2017-06-09.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: N/A
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (107)
    Domains in SCOPe 2.08: d5fw6a_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (107)
    Domains in SCOPe 2.08: d5fw6b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5fw6A (A:)
    gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
    eeefvegiykveidtksywkalgispfhehaevvftandsgprrytivallspysystta
    vvtnpke
    

    Sequence, based on observed residues (ATOM records): (download)
    >5fw6A (A:)
    cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytivallspysysttavvtnp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5fw6B (B:)
    gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
    eeefvegiykveidtksywkalgispfhehaevvftandsgprrytivallspysystta
    vvtnpke
    

    Sequence, based on observed residues (ATOM records): (download)
    >5fw6B (B:)
    cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytivallspysysttavvtnp