PDB entry 5fut

View 5fut on RCSB PDB site
Description: Human choline kinase a1 in complex with compound 4-(dimethylamino)-1-{4-[4-(4-{[4-(pyrrolidin- 1-yl)pyridinium-1-yl]methyl}phenyl)butyl]benzyl}pyridinium (compound BR25)
Class: transferase
Keywords: transferase, choline kinase, phosphatidyletanolamine, inhibitors
Deposited on 2016-01-29, released 2016-09-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-29, with a file datestamp of 2019-05-24.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: choline kinase alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5futa_
  • Heterogens: EDO, PQ7, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5futA (A:)
deqpeprtrrraylwckeflpgawrglredefhisvirgglsnmlfqcslpdttatlgde
prkvllrlygailqmrscnkegseqaqkenefqgaeamvlesvmfailaerslgpklygi
fpqgrleqfipsrrldteelslpdisaeiaekmatfhgmkmpfnkepkwlfgtmekylke
vlrikfteesrikklhkllsynlplelenlrsllestpspvvfchndcqegnilllegre
nsekqklmlidfeyssynyrgfdignhfcewmydysyekypffranirkyptkkqqlhfi
ssylpafqndfenlsteeksiikeemllevnrfalashflwglwsivqakissiefgymd
yaqarfdayfhqkrklgv

    Sequence, based on observed residues (ATOM records): (download) 
    >5futA (A:)
deqpeprtrrraylwckeflpgawrglredefhisvirgglsnmlfqcslpdttatlgde
prkvllrlyggaeamvlesvmfailaerslgpklygifpqgrleqfipsrrldteelslp
disaeiaekmatfhgmkmpfnkepkwlfgtmekylkevlrikfteesrikklhkllsynl
plelenlrsllestpspvvfchndcqegnilllegrensekqklmlidfeyssynyrgfd
ignhfcewmydysyekypffranirkyptkkqqlhfissylpafqndfenlsteeksiik
eemllevnrfalashflwglwsivqakissiefgymdyaqarfdayfhqkrklgv