PDB entry 5fpq

View 5fpq on RCSB PDB site
Description: Structure of Homo sapiens acetylcholinesterase phosphonylated by sarin.
Class: hydrolase
Keywords: hydrolase, signaling protein, acetylcholinesterase, sarin, hi-6, qm, density functional theory calculations, michaelis complex.
Deposited on 2015-12-02, released 2016-05-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-17, with a file datestamp of 2018-01-12.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholinesterase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fpqa_
  • Chain 'B':
    Compound: acetylcholinesterase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fpqb_
  • Heterogens: 1PE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fpqA (A:)
gredaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvd
attfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygg
gfysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalq
wvqenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgm
gearrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvp
vvdgdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraefla
gvrvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaq
garvyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywa
nfartgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpklls
at

    Sequence, based on observed residues (ATOM records): (download) 
    >5fpqA (A:)
edaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdat
tfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggf
ysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwv
qenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmge
arrratqlahlvgcpggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvdgdf
lsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvrvgv
pqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarvya
yvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfartg
dpneprdpqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5fpqB (B:)
gredaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvd
attfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygg
gfysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalq
wvqenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgm
gearrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvp
vvdgdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraefla
gvrvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaq
garvyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywa
nfartgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpklls
at

    Sequence, based on observed residues (ATOM records): (download) 
    >5fpqB (B:)
edaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdat
tfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggf
ysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwv
qenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmge
arrratqlahlvgcpndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvdgdfls
dtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvrvgvpq
vsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarvyayv
fehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfartgdp
neprdpqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsa