PDB entry 5fp5
View 5fp5 on RCSB PDB site
Description: Structure of cyclin-dependent kinase 2 with small-molecule ligand 4- fluorobenzoic acid (AT222) in an alternate binding site.
Class: transferase
Keywords: transferase, kinase, mitosis, cell cycle, fragment screening, alternate binding site.
Deposited on
2015-11-27, released
2015-12-09
The last revision prior to the SCOPe 2.05 freeze date was dated
2015-12-09, with a file datestamp of
2015-12-04.
Experiment type: XRAY
Resolution: 2.16 Å
R-factor: N/A
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cyclin-dependent kinase 2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d5fp5a_ - Heterogens: 1Y6, ACE, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5fp5A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>5fp5A (A:)
menfqkvekigegygvvykarnkltgevvalkkitaireisllkelnhpnivklldviht
lylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlkpqnlli
ntegaikladfgltlwyrapeillgckyystavdiwslgcifaemvtrralfpgdseidq
lfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsllsqmlhydp
nkrisakaalahpffqdvtkpvph