PDB entry 5fns

View 5fns on RCSB PDB site
Description: Structure of the Keap1 Kelch domain in complex with a small molecule inhibitor.
Class: transcription
Keywords: transcription, trasncription, keap1, nrf2, oxidative stress
Deposited on 2015-11-16, released 2016-04-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-04-13, with a file datestamp of 2016-04-08.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kelch-like ECH-associated protein 1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5fnsa_
  • Heterogens: XYY, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fnsA (A:)
gpkvgrliytaggyfrqslsyleaynpsngswlrladlqvprsglagcvvggllyavggr
nnspdgntdssaldcynpmtnqwspcasmsvprnrigvgvidghiyavggshgcihhssv
eryeperdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmi
tpmntirsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfvapmrhhrsalgit
vhqgkiyvlggydghtfldsvecydpdsdtwsevtrmtsgrsgvgvavtmepcrkqidqq
nctc

    Sequence, based on observed residues (ATOM records): (download) 
    >5fnsA (A:)
grliytaggyfrqslsyleaynpsngswlrladlqvprsglagcvvggllyavggrnnsp
dgntdssaldcynpmtnqwspcasmsvprnrigvgvidghiyavggshgcihhssverye
perdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitpmn
tirsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfvapmrhhrsalgitvhqg
kiyvlggydghtfldsvecydpdsdtwsevtrmtsgrsgvgvavtmepc