PDB entry 5fh8

View 5fh8 on RCSB PDB site
Description: Crystal structure of the fifth bromodomain of human PB1 in complex with compound 28
Class: transcription
Keywords: PBRM1, BRG1-associated factor 180, transcription, chromatin remodeling
Deposited on 2015-12-21, released 2016-06-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-06-08, with a file datestamp of 2016-06-03.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein polybromo-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PBRM1, BAF180, PB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fh8a_
  • Chain 'B':
    Compound: Protein polybromo-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PBRM1, BAF180, PB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fh8b_
  • Chain 'C':
    Compound: Protein polybromo-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PBRM1, BAF180, PB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fh8c_
  • Chain 'D':
    Compound: Protein polybromo-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PBRM1, BAF180, PB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fh8d_
  • Heterogens: 5XK, DMS, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fh8A (A:)
smsgispkkskymtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikk
pmdmekirshmmankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrd
legd

    Sequence, based on observed residues (ATOM records): (download) 
    >5fh8A (A:)
skymtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikkpmdmekirs
hmmankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrdl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5fh8B (B:)
smsgispkkskymtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikk
pmdmekirshmmankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrd
legd

    Sequence, based on observed residues (ATOM records): (download) 
    >5fh8B (B:)
kymtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikkpmdmekirsh
mmankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrdl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5fh8C (C:)
smsgispkkskymtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikk
pmdmekirshmmankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrd
legd

    Sequence, based on observed residues (ATOM records): (download) 
    >5fh8C (C:)
ymtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikkpmdmekirshm
mankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5fh8D (D:)
smsgispkkskymtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikk
pmdmekirshmmankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrd
legd

    Sequence, based on observed residues (ATOM records): (download) 
    >5fh8D (D:)
ymtpmqqklnevyeavknytdkrgrrlsaiflrlpsrselpdyyltikkpmdmekirshm
mankyqdidsmvedfvmmfnnactynepesliykdalvlhkvlletrrd