PDB entry 5fbo

View 5fbo on RCSB PDB site
Description: BTK-inhibitor co-structure
Class: TRANSFERASE/TRANSFERASE inhibitor
Keywords: kinase, phosphatase, transferase-transferase inhibitor complex
Deposited on 2015-12-14, released 2016-03-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-04-18, with a file datestamp of 2018-04-13.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase BTK
    Species: Homo sapiens [TaxId:9606]
    Gene: BTK, AGMX1, ATK, BPK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fboa_
  • Heterogens: 5WH, 5WE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fboA (A:)
glgygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakv
mmnlsheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvcea
meyleskqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsppev
lmyskfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvyt
imyscwhekaderptfkillsnildvmdees

    Sequence, based on observed residues (ATOM records): (download) 
    >5fboA (A:)
ygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmn
lsheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceamey
leskqflhrdlaarnclvndqgvvkvsdfglsskfpvrwsppevlmyskfssksdiwafg
vlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimyscwhekaderptf
killsnildvmdees