PDB entry 5f6v
View 5f6v on RCSB PDB site
Description: Crystal structure of Ubc9 (K48/K49A/E54A) complexed with Fragment 1 (biphenol from fragment cocktail screen)
Class: LIGASE/LIGASE inhibitor
Keywords: Ubc9, Fragment drug design, sumoylation, LIGASE-LIGASE inhibitor complex
Deposited on
2015-12-07, released
2016-04-27
The last revision prior to the SCOPe 2.06 freeze date was dated
2016-04-27, with a file datestamp of
2016-04-22.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: SUMO-conjugating enzyme UBC9
Species: Homo sapiens [TaxId:9606]
Gene: UBE2I, UBC9, UBCE9
Database cross-references and differences (RAF-indexed):
- Uniprot P63279 (0-End)
- engineered mutation (46-47)
- engineered mutation (52)
Domains in SCOPe 2.06: d5f6va_ - Heterogens: 5VL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5f6vA (A:)
sgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgaagtpwagglfklr
mlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqelln
epniqdpaqaeaytiycqnrveyekrvraqakkfaps
Sequence, based on observed residues (ATOM records): (download)
>5f6vA (A:)
sgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgaagtpwagglfklr
mlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqelln
epniqdpaqaeaytiycqnrveyekrvraqakkfap