PDB entry 5f2c

View 5f2c on RCSB PDB site
Description: Thermostable aldehyde dehydrogenase from Pyrobaculum sp. 1860 crystallized in microgravity (complex with NADP+)
Class: oxidoreductase
Keywords: Thermostable aldehyde dehydrogenase, oxidoreductase
Deposited on 2015-12-01, released 2016-12-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-06-20, with a file datestamp of 2018-06-15.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum ferrireducens [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f2ca_
  • Chain 'B':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum ferrireducens [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f2cb_
  • Chain 'C':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum ferrireducens [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f2cc_
  • Chain 'D':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum ferrireducens [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f2cd_
  • Chain 'E':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum ferrireducens [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f2ce_
  • Chain 'F':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum ferrireducens [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f2cf_
  • Chain 'G':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum ferrireducens [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f2cg_
  • Chain 'H':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum ferrireducens [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f2ch_
  • Heterogens: NAP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5f2cA (A:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5f2cA (A:)
lnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawa
nipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarh
yqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdt
pvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaaka
agtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkf
ieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnf
fepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnraf
riaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrr
fpipsalk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5f2cB (B:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5f2cB (B:)
mkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawanip
airraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarhyqg
rvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdtpvt
gwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaakaagt
lktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkfier
yvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnffep
aifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnrafria
eavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrrfpi
psal

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5f2cC (C:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5f2cC (C:)
idlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealka
wanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaela
rhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpas
dtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaa
kaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavad
kfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswg
nffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnr
afriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrt
rrfpipsalk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5f2cD (D:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5f2cD (D:)
kvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawanipa
irraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarhyqgr
vlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdtpvtg
wliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaakaagtl
ktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkfiery
vhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnffepa
ifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnrafriae
avesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrrfpip
salk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5f2cE (E:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5f2cE (E:)
mkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawanip
airraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarhyqg
rvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdtpvt
gwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaakaagt
lktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkfier
yvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnffep
aifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnrafria
eavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrrfpi
psalk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5f2cF (F:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5f2cF (F:)
idlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealka
wanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaela
rhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpas
dtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaa
kaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavad
kfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswg
nffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnr
afriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrt
rrfpipsalk

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5f2cG (G:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5f2cG (G:)
mkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawanip
airraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarhyqg
rvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdtpvt
gwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaakaagt
lktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkfier
yvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnffep
aifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnrafria
eavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrrfpi
psal

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5f2cH (H:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5f2cH (H:)
lnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawa
nipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarh
yqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdt
pvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaaka
agtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkf
ieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnf
fepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnraf
riaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrr
fpipsalk