PDB entry 5f28

View 5f28 on RCSB PDB site
Description: Crystal structure of FAT domain of Focal Adhesion Kinase (FAK) bound to the transcription factor MEF2C
Class: Transcription, protein binding
Keywords: Transcription Factor, Kinase, Cardiovascular disease, Transcription, protein binding
Deposited on 2015-12-01, released 2016-07-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mef2c
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f28a_
  • Chain 'B':
    Compound: mef2c
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f28b_
  • Chain 'C':
    Compound: mef2c
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f28c_
  • Chain 'D':
    Compound: mef2c
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f28d_
  • Chain 'E':
    Compound: Focal adhesion kinase 1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f28e_
  • Chain 'F':
    Compound: Focal adhesion kinase 1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f28f_
  • Chain 'G':
    Compound: Focal adhesion kinase 1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5f28g_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5f28A (A:)
mgrkkiqitrimdernrqvtftkrkfglmkkayelsvlcdceialiifnstnklfqyast
dmdkvllkyteynephesrtnsdivealnkkenkg

    Sequence, based on observed residues (ATOM records): (download) 
    >5f28A (A:)
ftkrkfglmkkayelsvlcdceialiifnstnklfqyastdmdkvllkyteynephesrt
nsdivealnk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5f28B (B:)
mgrkkiqitrimdernrqvtftkrkfglmkkayelsvlcdceialiifnstnklfqyast
dmdkvllkyteynephesrtnsdivealnkkenkg

    Sequence, based on observed residues (ATOM records): (download) 
    >5f28B (B:)
vtftkrkfglmkkayelsvlcdceialiifnstnklfqyastdmdkvllkyteynephes
rtnsdivealnkk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5f28C (C:)
mgrkkiqitrimdernrqvtftkrkfglmkkayelsvlcdceialiifnstnklfqyast
dmdkvllkyteynephesrtnsdivealnkkenkg

    Sequence, based on observed residues (ATOM records): (download) 
    >5f28C (C:)
tftkrkfglmkkayelsvlcdceialiifnstnklfqyastdmdkvllkyteynephesr
tnsdivealnkk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5f28D (D:)
mgrkkiqitrimdernrqvtftkrkfglmkkayelsvlcdceialiifnstnklfqyast
dmdkvllkyteynephesrtnsdivealnkkenkg

    Sequence, based on observed residues (ATOM records): (download) 
    >5f28D (D:)
tftkrkfglmkkayelsvlcdceialiifnstnklfqyastdmdkvllkyteynephesr
tnsdivealnkk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5f28E (E:)
lqpqeisppptanldrsndkvyenvtglvkaviemsskiqpappeeyvpmvkevglalrt
llatvdetipalpasthreiemaqkllnsdlgeliskmklaqqyvmtslqqeykkqmlta
ahalavdaknlldvidqarlkmlgqtrph

    Sequence, based on observed residues (ATOM records): (download) 
    >5f28E (E:)
ldrsndkvyenvtglvkaviemsskiqpappeeyvpmvkevglalrtllatvdetipalp
asthreiemaqkllnsdlgeliskmklaqqyvmtslqqeykkqmltaahalavdaknlld
vidqarlk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5f28F (F:)
lqpqeisppptanldrsndkvyenvtglvkaviemsskiqpappeeyvpmvkevglalrt
llatvdetipalpasthreiemaqkllnsdlgeliskmklaqqyvmtslqqeykkqmlta
ahalavdaknlldvidqarlkmlgqtrph

    Sequence, based on observed residues (ATOM records): (download) 
    >5f28F (F:)
ldrsndkvyenvtglvkaviemsskiqpappeeyvpmvkevglalrtllatvdetipalp
asthreiemaqkllnsdlgeliskmklaqqyvmtslqqeykkqmltaahalavdaknlld
vidqarlk

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5f28G (G:)
lqpqeisppptanldrsndkvyenvtglvkaviemsskiqpappeeyvpmvkevglalrt
llatvdetipalpasthreiemaqkllnsdlgeliskmklaqqyvmtslqqeykkqmlta
ahalavdaknlldvidqarlkmlgqtrph

    Sequence, based on observed residues (ATOM records): (download) 
    >5f28G (G:)
nldrsndkvyenvtglvkaviemsskiqpappeeyvpmvkevglalrtllatvdetipal
pasthreiemaqkllnsdlgeliskmklaqqyvmtslqqeykkqmltaahalavdaknll
dvidqarlkmlgq