PDB entry 5ewa

View 5ewa on RCSB PDB site
Description: Crystal structure of the metallo-beta-lactamase IMP-1 in complex with the bisthiazolidine inhibitor L-VC26
Class: hydrolase
Keywords: inhibitor, carbapenemase, antibiotic resistance, hydrolase
Deposited on 2015-11-20, released 2016-06-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-07-20, with a file datestamp of 2016-07-15.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-lactamase imp-1
    Species: Serratia marcescens [TaxId:615]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ewaa_
  • Chain 'B':
    Compound: beta-lactamase imp-1
    Species: Serratia marcescens [TaxId:615]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ewab_
  • Chain 'C':
    Compound: beta-lactamase imp-1
    Species: Serratia marcescens [TaxId:615]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ewac_
  • Chain 'D':
    Compound: beta-lactamase imp-1
    Species: Serratia marcescens [TaxId:615]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ewad_
  • Heterogens: ZN, 9BZ, EDO, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ewaA (A:)
gpaeslpdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdtek
lvtwfvergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsf
sgvnywlvknkievfypgpghtpdnvvvwlperkilfggcfikpyglgnlgdanieawpk
sakllkskygkaklvvpshsevgdasllkltleqavkglneskkpskpsn

    Sequence, based on observed residues (ATOM records): (download) 
    >5ewaA (A:)
slpdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdteklvtw
fvergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsfsgvn
ywlvknkievfypgpghtpdnvvvwlperkilfggcfikpyglgnlgdanieawpksakl
lkskygkaklvvpshsevgdasllkltleqavkglnesk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ewaB (B:)
gpaeslpdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdtek
lvtwfvergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsf
sgvnywlvknkievfypgpghtpdnvvvwlperkilfggcfikpyglgnlgdanieawpk
sakllkskygkaklvvpshsevgdasllkltleqavkglneskkpskpsn

    Sequence, based on observed residues (ATOM records): (download) 
    >5ewaB (B:)
slpdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdteklvtw
fvergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsfsgvn
ywlvknkievfypgpghtpdnvvvwlperkilfggcfikpyglgnlgdanieawpksakl
lkskygkaklvvpshsevgdasllkltleqavkglnesk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5ewaC (C:)
gpaeslpdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdtek
lvtwfvergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsf
sgvnywlvknkievfypgpghtpdnvvvwlperkilfggcfikpyglgnlgdanieawpk
sakllkskygkaklvvpshsevgdasllkltleqavkglneskkpskpsn

    Sequence, based on observed residues (ATOM records): (download) 
    >5ewaC (C:)
slpdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdteklvtw
fvergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsfsgvn
ywlvknkievfypgpghtpdnvvvwlperkilfggcfikpyglgnlgdanieawpksakl
lkskygkaklvvpshsevgdasllkltleqavkglneskkps

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5ewaD (D:)
gpaeslpdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdtek
lvtwfvergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsf
sgvnywlvknkievfypgpghtpdnvvvwlperkilfggcfikpyglgnlgdanieawpk
sakllkskygkaklvvpshsevgdasllkltleqavkglneskkpskpsn

    Sequence, based on observed residues (ATOM records): (download) 
    >5ewaD (D:)
slpdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdteklvtw
fvergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsfsgvn
ywlvknkievfypgpghtpdnvvvwlperkilfggcfikpyglgnlgdanieawpksakl
lkskygkaklvvpshsevgdasllkltleqavkglnesk