PDB entry 5evd

View 5evd on RCSB PDB site
Description: Crystal structure of the metallo-beta-lactamase L1 in complex with the bisthiazolidine inhibitor D-VC26
Class: hydrolase
Keywords: inhibitor, carbapenemase, antibiotic resistance, hydrolase
Deposited on 2015-11-19, released 2016-06-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-07-20, with a file datestamp of 2016-07-15.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Metallo-beta-lactamase L1
    Species: Stenotrophomonas maltophilia [TaxId:40324]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5evda_
  • Heterogens: VC2, ZN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5evdA (A:)
    gpaevplpqlraytvdaswlqpmaplqiadhtwqigtedltallvqtpdgavlldggmpq
    mashlldnmkargvtprdlrlillshahadhagpvaelkrrtgakvaanaesavllargg
    sddlhfgdgityppanadrivmdgevitvggivftahfmaghtpgstawtwtdtrngkpv
    riayadslsapgyqlqgnpryphliedyrrsfatvralpcdvlltphpgasnwdyaagar
    agakaltckayadaaeqkfdgqlaketagar
    

    Sequence, based on observed residues (ATOM records): (download)
    >5evdA (A:)
    aevplpqlraytvdaswlqpmaplqiadhtwqigtedltallvqtpdgavlldggmpqma
    shlldnmkargvtprdlrlillshahadhagpvaelkrrtgakvaanaesavllarggsd
    dlhfgdgityppanadrivmdgevitvggivftahfmaghtpgstawtwtdtrngkpvri
    ayadslsapgyqlqgnpryphliedyrrsfatvralpcdvlltphpgasnwdyaagarag
    akaltckayadaaeqkfdgqlaketag