PDB entry 5eug

View 5eug on RCSB PDB site
Description: crystallographic and enzymatic studies of an active site variant h187q of escherichia coli uracil DNA glycosylase: crystal structures of mutant h187q and its uracil complex
Class: hydrolase
Keywords: glycosylase
Deposited on 1998-12-27, released 1999-07-23
The last revision prior to the SCOP 1.75 freeze date was dated 2000-06-23, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.178
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (glycosylase)
    Species: Escherichia coli
    Gene: UNG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12295 (Start-228)
      • engineered (186)
      • conflict (212)
    Domains in SCOP 1.75: d5euga_
  • Heterogens: URA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5eugA (A:)
maneltwhdvlaeekqqpyflntlqtvaserqsgvtiyppqkdvfnafrftelgdvkvvi
lgqdpyhgpgqahglafsvrpgiaippsllnmykelentipgftrpnhgyleswarqgvl
llntvltvragqahshaslgwetftdkvislinqhregvvfllwgshaqkkgaiidkqrh
hvlkapqpsplsahrgffgcnhfvlanqwleqhgetpidwmpvlpaese

    Sequence, based on observed residues (ATOM records): (download) 
    >5eugA (A:)
ltwhdvlaeekqqpyflntlqtvaserqsgvtiyppqkdvfnafrftelgdvkvvilgqd
pyhgpgqahglafsvrpgiaippsllnmykelentipgftrpnhgyleswarqgvlllnt
vltvragqahshaslgwetftdkvislinqhregvvfllwgshaqkkgaiidkqrhhvlk
apqpsplsahrgffgcnhfvlanqwleqhgetpidwmpvlpaese