PDB entry 5etw

View 5etw on RCSB PDB site
Description: Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with NLG919 analogue
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: IDO1, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on 2015-11-18, released 2016-02-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-09-06, with a file datestamp of 2017-09-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Indoleamine 2,3-dioxygenase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: IDO1, IDO, INDO
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5etwa_
  • Chain 'B':
    Compound: Indoleamine 2,3-dioxygenase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: IDO1, IDO, INDO
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5etwb_
  • Heterogens: HEM, XNL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5etwA (A:)
mahamenswtiskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerve
klnmlsidhltdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklel
ppilvyadcvlanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikv
iptvfkamqmqerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgn
pqlsdglvyegfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymp
pahrnflcslesnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasq
qpkenktsedpskleakgtggtdlmnflktvrstteksllkeg

    Sequence, based on observed residues (ATOM records): (download) 
    >5etwA (A:)
iskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhl
tdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcv
lanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqm
qerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvye
gfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsl
esnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqggtdlmnflk
tvrstteksll

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5etwB (B:)
mahamenswtiskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerve
klnmlsidhltdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklel
ppilvyadcvlanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikv
iptvfkamqmqerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgn
pqlsdglvyegfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymp
pahrnflcslesnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasq
qpkenktsedpskleakgtggtdlmnflktvrstteksllkeg

    Sequence, based on observed residues (ATOM records): (download) 
    >5etwB (B:)
skeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhlt
dhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvl
anwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmq
erdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyeg
fwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsle
snpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipagtdlmnflktvrs
tteksllk