PDB entry 5ene
View 5ene on RCSB PDB site
Description: Crystal structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with 5-Amino-2-benzyl-1,3-oxazole-4-carbonitrile (SGC - Diamond I04-1 fragment screening)
Class: signaling protein
Keywords: bromodomain, PHIP, crystallographic fragment screen, transcription, Structural Genomics, Structural Genomics Consortium, SGC, signaling protein
Deposited on
2015-11-09, released
2016-04-27
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-07-11, with a file datestamp of
2018-07-06.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.49
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: PH-interacting protein
Species: Homo sapiens [TaxId:9606]
Gene: PHIP, WDR11
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5enea1, d5enea2 - Heterogens: 5Q8, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5eneA (A:)
yfqsmsydiqawkkqceellnlifqcedsepfrqpvdlleypdyrdiidtpmdfatvret
leagnyespmelckdvrlifsnskaytpskrsriysmslrlsaffeehissvlsdyksal
rfhkrntitkr
Sequence, based on observed residues (ATOM records): (download)
>5eneA (A:)
smsydiqawkkqceellnlifqcedsepfrqpvdlleypdyrdiidtpmdfatvretlea
gnyespmelckdvrlifsnskaytpskrsriysmslrlsaffeehissvlsdyksalrfh
krn