PDB entry 5eln

View 5eln on RCSB PDB site
Description: Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine
Class: ligase
Keywords: SSGCID, Lysine--tRNA ligase, Cryptosporidium parvum, ATP binding, aminoacylation, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, LIGASE
Deposited on 2015-11-04, released 2016-11-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-03, with a file datestamp of 2019-03-29.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine--tRNA ligase
    Species: Cryptosporidium parvum (strain Iowa II) [TaxId:353152]
    Gene: cgd4_2370
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5CR27 (21-End)
      • expression tag (20)
    Domains in SCOPe 2.08: d5elna1, d5elna2, d5elna3
  • Chain 'B':
    Compound: Lysine--tRNA ligase
    Species: Cryptosporidium parvum (strain Iowa II) [TaxId:353152]
    Gene: cgd4_2370
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5CR27 (21-End)
      • expression tag (20)
    Domains in SCOPe 2.08: d5elnb1, d5elnb2, d5elnb3
  • Chain 'C':
    Compound: Lysine--tRNA ligase
    Species: Cryptosporidium parvum (strain Iowa II) [TaxId:353152]
    Gene: cgd4_2370
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5CR27 (21-End)
      • expression tag (20)
    Domains in SCOPe 2.08: d5elnc1, d5elnc2, d5elnc3
  • Chain 'D':
    Compound: Lysine--tRNA ligase
    Species: Cryptosporidium parvum (strain Iowa II) [TaxId:353152]
    Gene: cgd4_2370
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5CR27 (21-End)
      • expression tag (20)
    Domains in SCOPe 2.08: d5elnd1, d5elnd2, d5elnd3
  • Heterogens: LYS, EDO, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5elnA (A:)
    mahhhhhhmgtleaqtqgpgshytdnrykmmecikdagrpfyphkfkismslpayalkyg
    nvengyidkdttlslsgrvtsirssssklifydifceeqkvqiianimehdistgefsvs
    hseirrgdvvgftgfpgkskrgelslfsksvvllspcyhmlptaisglkdqevryrqryl
    dlmlneesrkvfklrsraikyirnyfdrlgflevetpmlnmiyggaaarpfityhnelet
    qlymriapelylkqlivggldkvyeigknfrnegidlthnpeftamefymayadyydlmd
    lteelisglvleihgslkipyhpdgpegkcieidfttpwkrfsfveeiesglgeklkrpl
    dsqenidfmvemcekheielphprtaaklldklaghfvetkctnpsfiidhpqtmsplak
    whrekpemterfelfvlgkelcnaytelneplqqrkffeqqadakasgdveacpidetfc
    lalehglpptggwglgidrlimfladknnikevilfpamrnvkqnaqhsnqhsgn
    

    Sequence, based on observed residues (ATOM records): (download)
    >5elnA (A:)
    shytdnrykmmecikdagrpfyphkfkismslpayalkygnvengyidkdttlslsgrvt
    sirssssklifydifceeqkvqiianimehdistgefsvshseirrgdvvgftgfpgksk
    rgelslfsksvvllspcyhmlptaisglkdqevryrqryldlmlneesrkvfklrsraik
    yirnyfdrlgflevetpmlnmiyggaaarpfityhneletqlymriapelylkqlivggl
    dkvyeigknfrnegidlthnpeftamefymayadyydlmdlteelisglvleihgslkip
    yhpdgpegkcieidfttpwkrfsfveeiesglgeklkrpldsqenidfmvemcekheiel
    phprtaaklldklaghfvetkctnpsfiidhpqtmsplakwhrekpemterfelfvlgke
    lcnaytelneplqqrkffeqqadakasgdveacpidetfclalehglpptggwglgidrl
    imfladknnikevilfpamrn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5elnB (B:)
    mahhhhhhmgtleaqtqgpgshytdnrykmmecikdagrpfyphkfkismslpayalkyg
    nvengyidkdttlslsgrvtsirssssklifydifceeqkvqiianimehdistgefsvs
    hseirrgdvvgftgfpgkskrgelslfsksvvllspcyhmlptaisglkdqevryrqryl
    dlmlneesrkvfklrsraikyirnyfdrlgflevetpmlnmiyggaaarpfityhnelet
    qlymriapelylkqlivggldkvyeigknfrnegidlthnpeftamefymayadyydlmd
    lteelisglvleihgslkipyhpdgpegkcieidfttpwkrfsfveeiesglgeklkrpl
    dsqenidfmvemcekheielphprtaaklldklaghfvetkctnpsfiidhpqtmsplak
    whrekpemterfelfvlgkelcnaytelneplqqrkffeqqadakasgdveacpidetfc
    lalehglpptggwglgidrlimfladknnikevilfpamrnvkqnaqhsnqhsgn
    

    Sequence, based on observed residues (ATOM records): (download)
    >5elnB (B:)
    shytdnrykmmecikdagrpfyphkfkismslpayalkygnvengyidkdttlslsgrvt
    sirssssklifydifceeqkvqiianimehdistgefsvshseirrgdvvgftgfpgksk
    rgelslfsksvvllspcyhmlptaisglkdqevryrqryldlmlneesrkvfklrsraik
    yirnyfdrlgflevetpmlnmiyggaaarpfityhneletqlymriapelylkqlivggl
    dkvyeigknfrnegidlthnpeftamefymayadyydlmdlteelisglvleihgslkip
    yhpdgpegkcieidfttpwkrfsfveeiesglgeklkrpldsqenidfmvemcekheiel
    phprtaaklldklaghfvetkctnpsfiidhpqtmsplakwhrekpemterfelfvlgke
    lcnaytelneplqqrkffeqqadakasgdveacpidetfclalehglpptggwglgidrl
    imfladknnikevilfpamrn
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >5elnC (C:)
    mahhhhhhmgtleaqtqgpgshytdnrykmmecikdagrpfyphkfkismslpayalkyg
    nvengyidkdttlslsgrvtsirssssklifydifceeqkvqiianimehdistgefsvs
    hseirrgdvvgftgfpgkskrgelslfsksvvllspcyhmlptaisglkdqevryrqryl
    dlmlneesrkvfklrsraikyirnyfdrlgflevetpmlnmiyggaaarpfityhnelet
    qlymriapelylkqlivggldkvyeigknfrnegidlthnpeftamefymayadyydlmd
    lteelisglvleihgslkipyhpdgpegkcieidfttpwkrfsfveeiesglgeklkrpl
    dsqenidfmvemcekheielphprtaaklldklaghfvetkctnpsfiidhpqtmsplak
    whrekpemterfelfvlgkelcnaytelneplqqrkffeqqadakasgdveacpidetfc
    lalehglpptggwglgidrlimfladknnikevilfpamrnvkqnaqhsnqhsgn
    

    Sequence, based on observed residues (ATOM records): (download)
    >5elnC (C:)
    shytdnrykmmecikdagrpfyphkfkismslpayalkygnvengyidkdttlslsgrvt
    sirssssklifydifceeqkvqiianimehdistgefsvshseirrgdvvgftgfpgksk
    rgelslfsksvvllspcyhmlptaidqevryrqryldlmlneesrkvfklrsraikyirn
    yfdrlgflevetpmlnmiyggaaarpfityhneletqlymriapelylkqlivggldkvy
    eigknfrnegidlthnpeftamefymayadyydlmdlteelisglvleihgslkipyhpd
    gpegkcieidfttpwkrfsfveeiesglgeklkrpldsqenidfmvemcekheielphpr
    taaklldklaghfvetkctnpsfiidhpqtmsplakwhrekpemterfelfvlgkelcna
    ytelneplqqrkffeqqadakasgdveacpidetfclalehglpptggwglgidrlimfl
    adknnikevilfpamrn
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >5elnD (D:)
    mahhhhhhmgtleaqtqgpgshytdnrykmmecikdagrpfyphkfkismslpayalkyg
    nvengyidkdttlslsgrvtsirssssklifydifceeqkvqiianimehdistgefsvs
    hseirrgdvvgftgfpgkskrgelslfsksvvllspcyhmlptaisglkdqevryrqryl
    dlmlneesrkvfklrsraikyirnyfdrlgflevetpmlnmiyggaaarpfityhnelet
    qlymriapelylkqlivggldkvyeigknfrnegidlthnpeftamefymayadyydlmd
    lteelisglvleihgslkipyhpdgpegkcieidfttpwkrfsfveeiesglgeklkrpl
    dsqenidfmvemcekheielphprtaaklldklaghfvetkctnpsfiidhpqtmsplak
    whrekpemterfelfvlgkelcnaytelneplqqrkffeqqadakasgdveacpidetfc
    lalehglpptggwglgidrlimfladknnikevilfpamrnvkqnaqhsnqhsgn
    

    Sequence, based on observed residues (ATOM records): (download)
    >5elnD (D:)
    shytdnrykmmecikdagrpfyphkfkismslpayalkygnvengyidkdttlslsgrvt
    sirssssklifydifceeqkvqiianimehdistgefsvshseirrgdvvgftgfpgksk
    rgelslfsksvvllspcyhmlptaiqevryrqryldlmlneesrkvfklrsraikyirny
    fdrlgflevetpmlnmiyggaaarpfityhneletqlymriapelylkqlivggldkvye
    igknfrnegidlthnpeftamefymayadyydlmdlteelisglvleihgslkipyhpdg
    pegkcieidfttpwkrfsfveeiesglgeklkrpldsqenidfmvemcekheielphprt
    aaklldklaghfvetkctnpsfiidhpqtmsplakwhrekpemterfelfvlgkelcnay
    telneplqqrkffeqqadakasgdveacpidetfclalehglpptggwglgidrlimfla
    dknnikevilfpamrn