PDB entry 5ekc

View 5ekc on RCSB PDB site
Description: Thermostable aldehyde dehydrogenase from Pyrobaculum sp.1860 complexed with NADP+
Class: oxidoreductase
Keywords: Aldehyde dehydrogenase, thermostable, OXIDOREDUCTASE
Deposited on 2015-11-03, released 2016-11-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-11-16, with a file datestamp of 2016-11-11.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum sp. 1860 [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ekca_
  • Chain 'B':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum sp. 1860 [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ekcb_
  • Chain 'C':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum sp. 1860 [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ekcc_
  • Chain 'D':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum sp. 1860 [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ekcd_
  • Chain 'E':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum sp. 1860 [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ekce_
  • Chain 'F':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum sp. 1860 [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ekcf_
  • Chain 'G':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum sp. 1860 [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ekcg_
  • Chain 'H':
    Compound: aldehyde dehydrogenase
    Species: Pyrobaculum sp. 1860 [TaxId:1104324]
    Gene: P186_1147
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ekch_
  • Heterogens: NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ekcA (A:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5ekcA (A:)
mkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawanip
airraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarhyqg
rvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdtpvt
gwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaakaagt
lktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkfier
yvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnffep
aifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnrafria
eavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrrfpi
psalk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ekcB (B:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5ekcB (B:)
imkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawani
pairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarhyq
grvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdtpv
tgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaakaag
tlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkfie
ryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnffe
paifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnrafri
aeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrrfp
ipsal

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5ekcC (C:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5ekcC (C:)
vanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawanipai
rraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarhyqgrv
lqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdtpvtgw
liaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaakaagtlk
tvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkfieryv
hyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnffepai
fvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnrafriaea
vesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrrfpips
alk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5ekcD (D:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5ekcD (D:)
kvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawanipa
irraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarhyqgr
vlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdtpvtg
wliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaakaagtl
ktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkfiery
vhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnffepa
ifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnrafriae
avesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrrfpip
salk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5ekcE (E:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5ekcE (E:)
idlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealka
wanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaela
rhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpas
dtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaa
kaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavad
kfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswg
nffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnr
afriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrt
rrfpipsalk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5ekcF (F:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5ekcF (F:)
vanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawanipai
rraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarhyqgrv
lqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdtpvtgw
liaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaakaagtlk
tvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkfieryv
hyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnffepai
fvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnrafriaea
vesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrrfpips
al

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5ekcG (G:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5ekcG (G:)
mkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawanip
airraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarhyqg
rvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdtpvt
gwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaakaagt
lktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkfier
yvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnffep
aifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnrafria
eavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrrfpi
psal

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5ekcH (H:)
midlnimkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealk
awanipairraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaael
arhyqgrvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpa
sdtpvtgwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreia
akaagtlktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkava
dkfieryvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrsw
gnffepaifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvn
rafriaeavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlr
trrfpipsalk

    Sequence, based on observed residues (ATOM records): (download) 
    >5ekcH (H:)
mkvanyingefkepstgafqvktspvdgskiaevprsgredareaidsafealkawanip
airraeylykmlevfrqmkedfmkiltvegggtyrkvwgevvfterliqnaaelarhyqg
rvlqsdsestisvvfkrskgvvgvitpwnyplsismkkiahtlavgntvvykpasdtpvt
gwliaqmvakaglpkgvfnlvigpgpvvgeeivthkrvahvtftgesstgreiaakaagt
lktvtlelggsdpliilddvdvdyaarlavfaslfhqgqictsakriivhkavadkfier
yvhyvkmlriddprkdekvdlgplinerqvalmkefvddavsrggrlliggrswgnffep
aifvdvdrnfrimreevfgpvrpivvvenddqavevandtdyglsgavltnnvnrafria
eavesgmfhindvtfleeshvpfggikasgvgreggewsfhettydrwvtvtlrtrrfpi
psalk