PDB entry 5eiz

View 5eiz on RCSB PDB site
Description: Crystal structure of Y99A mutant of human macrophage migration inhibitory factor
Class: isomerase
Keywords: Isomerase, surface, mutation
Deposited on 2015-10-30, released 2015-11-11
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-11-11, with a file datestamp of 2015-11-06.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
    • engineered mutation (98)
  Domains in SCOPe 2.05: d5eiza_
• Chain 'B':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
    • engineered mutation (98)
  Domains in SCOPe 2.05: d5eizb_
• Chain 'C':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
    • engineered mutation (98)
  Domains in SCOPe 2.05: d5eizc_
• Heterogens: GOL, SO4, IPA, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5eizA (A:)
  pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyadmnaanvgwnnstfa
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5eizB (B:)
  pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyadmnaanvgwnnstfa
  

  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5eizC (C:)
  pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyadmnaanvgwnnstfa