PDB entry 5ea2

View 5ea2 on RCSB PDB site
Description: Crystal Structure of Holo NAD(P)H dehydrogenase, quinone 1
Class: oxidoreductase
Keywords: NQO1, two-electron reduction of Quinone, NAD(P)H dehydrogenase, OXIDOREDUCTASE
Deposited on 2015-10-15, released 2016-02-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nad(p)h dehydrogenase [quinone] 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NQO1, DIA4, NMOR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ea2a_
  • Chain 'C':
    Compound: nad(p)h dehydrogenase [quinone] 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NQO1, DIA4, NMOR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15559 (3-275)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d5ea2c1, d5ea2c2
  • Chain 'E':
    Compound: nad(p)h dehydrogenase [quinone] 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NQO1, DIA4, NMOR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ea2e_
  • Chain 'G':
    Compound: nad(p)h dehydrogenase [quinone] 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NQO1, DIA4, NMOR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ea2g_
  • Heterogens: FAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ea2A (A:)
gphmvgrralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkdit
gklkdpanfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwf
ervfigefaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgil
hfcgfqvlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagf
lmkkevqdeeknkkfglsvghhlgksiptdnqikar

    Sequence, based on observed residues (ATOM records): (download) 
    >5ea2A (A:)
mvgrralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgkl
kdpanfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwferv
figefaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfc
gfqvlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmk
kevqdeeknkkfglsvghhlgksiptdnqikar

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5ea2C (C:)
gphmvgrralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkdit
gklkdpanfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwf
ervfigefaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgil
hfcgfqvlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagf
lmkkevqdeeknkkfglsvghhlgksiptdnqikar

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5ea2E (E:)
gphmvgrralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkdit
gklkdpanfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwf
ervfigefaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgil
hfcgfqvlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagf
lmkkevqdeeknkkfglsvghhlgksiptdnqikar

    Sequence, based on observed residues (ATOM records): (download) 
    >5ea2E (E:)
rralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgklkdp
anfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwfervfig
efaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfcgfq
vlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmkkev
qdeeknkkfglsvghhlgksiptdnqikar

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5ea2G (G:)
gphmvgrralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkdit
gklkdpanfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwf
ervfigefaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgil
hfcgfqvlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagf
lmkkevqdeeknkkfglsvghhlgksiptdnqikar

    Sequence, based on observed residues (ATOM records): (download) 
    >5ea2G (G:)
grralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgklkd
panfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwfervfi
gefaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfcgf
qvlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmkke
vqdeeknkkfglsvghhlgksiptdnqikar