PDB entry 5e95

View 5e95 on RCSB PDB site
Description: Crystal Structure of Mb(NS1)/H-Ras Complex
Class: signaling protein/inhibitor
Keywords: H-Ras, Monobody, Inhibitor, Complex, SIGNALING PROTEIN-INHIBITOR complex
Deposited on 2015-10-14, released 2016-11-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01112 (2-167)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d5e95a1, d5e95a2
  • Chain 'B':
    Compound: Mb(NS1)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5E95 (Start-96)
    Domains in SCOPe 2.08: d5e95b_
  • Heterogens: GDP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5e95A (A:)
gsmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildt
agqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkc
dlaartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5e95B (B:)
gsvssvptklevvaatptslliswdapavtvdyyvitygetggnspvqkfevpgskstat
isglkpgvdytitvyawgwhgqvyyymgspisinyrt

    Sequence, based on observed residues (ATOM records): (download) 
    >5e95B (B:)
ssvptklevvaatptslliswdapavtvdyyvitygetggpvqkfevpgskstatisglk
pgvdytitvyawgwhgqvyyymgspisinyrt