PDB entry 5e4n

View 5e4n on RCSB PDB site
Description: 3-Deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis with D-tyrosine bound in the tyrosine and phenylalanine binding sites
Class: transferase
Keywords: amino acid, allosteric regulation, shikimate pathway, 3-Deoxy-D-arabino-heptulosonate 7-phosphate synthase, TRANSFERASE
Deposited on 2015-10-06, released 2016-06-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-06-01, with a file datestamp of 2016-05-27.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: aroG_1, ERS024751_03564, ERS094182_00944, ERS124362_02783
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5e4na_
  • Chain 'B':
    Compound: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: aroG_1, ERS024751_03564, ERS094182_00944, ERS124362_02783
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5e4nb_
  • Heterogens: SO4, CL, MN, DTY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5e4nA (A:)
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqv
ianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatg
hqviwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvt
eclggaqdisetdlagryetacdprlntqqslelaflvaemlrd

    Sequence, based on observed residues (ATOM records): (download) 
    >5e4nA (A:)
mnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtv
pseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmp
vvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaam
nlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqt
aeiyashealvldyeramlrlsdgepqlfdlsahtvwigertrqidgahiafaqvianpv
gvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqviw
qcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvteclgg
aqdisetdlagryetacdprlntqqslelaflvaemlrd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5e4nB (B:)
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqv
ianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatg
hqviwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvt
eclggaqdisetdlagryetacdprlntqqslelaflvaemlrd

    Sequence, based on observed residues (ATOM records): (download) 
    >5e4nB (B:)
mnwtvdipilpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtvpseiv
rlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmpvvkva
riagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaamnlvra
ltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqtaeiya
shealvldyeramlrlsdgepqlfdlsahtvwigertrqidgahiafaqvianpvgvklg
pnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqviwqcdpm
hgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvteclggaqdis
etdlagryetacdprlntqqslelaflvaemlrd