PDB entry 5e2r

View 5e2r on RCSB PDB site
Description: The crystal structure of the human carbonic anhydrase II in complex with a 1,1'-biphenyl-4-sulfonamide inhibitor
Class: lyase
Keywords: 1'-biphenyl-4-sulfonamide, lyase, complex, inhibitor
Deposited on 2015-10-01, released 2015-11-04
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-11-04, with a file datestamp of 2015-10-30.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00918 (2-261)
      • expression tag (1)
    Domains in SCOPe 2.05: d5e2ra_
  • Heterogens: ZN, 520, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5e2rA (A:)
mgmshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslr
ilnnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaael
hlvhwntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnf
dprgllpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepee
lmvdnwrpaqplknrqikasfk

    Sequence, based on observed residues (ATOM records): (download) 
    >5e2rA (A:)
gmshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslri
lnnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelh
lvhwntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfd
prgllpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeel
mvdnwrpaqplknrqikasfk