PDB entry 5dri

View 5dri on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-hydroxy-4-(1H-indol-5-yl)-4-oxobut-2-enoic acid inhibitor
Class: transferase
Keywords: Acetyltransferase, TRANSFERASE
Deposited on 2015-09-15, released 2016-09-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: malate synthase g
    Species: Mycobacterium tuberculosis [TaxId:419947]
    Gene: glcB, MRA_1848
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5U3K4
      • engineered mutation (618)
    Domains in SCOPe 2.08: d5dria_
  • Heterogens: MG, 5EQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5driA (A:)
mtdrvsvgnlriarvlydfvnnealpgtdidpdsfwagvdkvvadltpqnqallnardel
qaqidkwhrrrviepidmdayrqflteigyllpepddftittsgvdaeitttagpqlvvp
vlnarfalnaanarwgslydalygtdvipetdgaekgptynkvrgdkviayarkflddsv
plssgsfgdatgftvqdgqlvvalpdkstglanpgqfagytgaaesptsvllinhglhie
ilidpesqvgttdragvkdvilesaittimdfedsvaavdaadkvlgyrnwlglnkgdla
aavdkdgtaflrvlnrdrnytapgggqftlpgrslmfvrnvghlmtndaivdtdgsevfe
gimdalftgliaihglkasdvngplinsrtgsiyivkpkmhgpaevaftcelfsrvedvl
glpqntmkigimdeerrttvnlkacikaaadrvvfintgfldrtgdeihtsmeagpmvrk
gtmksqpwilayedhnvdaglaagfsgraqvgkgmwtmtelmadmvetkiaqpragasta
wvpsptaatlhalhyhqvdvaavqqglagkrratieqlltiplakelawapdeireevdn
ncqsilgyvvrwvdqgvgaskvpdihdvalmedratlrissqllanwlrhgvitsadvra
slermaplvdrqnagdvayrpmapnfddsiaflaaqelilsgaqqpngytepilhrrrre
fkaraaekpapsdragddaar

    Sequence, based on observed residues (ATOM records): (download) 
    >5driA (A:)
tdrvsvgnlriarvlydfvnnealpgtdidpdsfwagvdkvvadltpqnqallnardelq
aqidkwhrrrpidmdayrqflteigyllpepddftittsgvdaeitttagpqlvvpvlna
rfalnaanarwgslydalygtdvipetdgaekgptynkvrgdkviayarkflddsvplss
gsfgdatgftvqdgqlvvalpdkstglanpgqfagytgaaesptsvllinhglhieilid
pesqvgttdragvkdvilesaittimdfedsvaavdaadkvlgyrnwlglnkgdlaarvl
nrdrnytapgggqftlpgrslmfvrnvghlmtndaivdtdgsevfegimdalftgliaih
glkasdvgplinsrtgsiyivkpkmhgpaevaftcelfsrvedvlglpqntmkigimdee
rrttvnlkacikaaadrvvfintgfldrtgdeihtsmeagpmvrkgtmksqpwilayedh
nvdaglaagfsgraqvgkgmwtmtelmadmvetkiaqpragastawvpsptaatlhalhy
hqvdvaavqqglagkrratieqlltiplakelawapdeireevdnncqsilgyvvrwvdq
gvgaskvpdihdvalmedratlrissqllanwlrhgvitsadvraslermaplvdrqnay
rpmapnfddsiaflaaqelilsgaqqpngytepilhrrrrefkaraae