PDB entry 5dls

View 5dls on RCSB PDB site
Description: Identification of Novel, in vivo Active Chk1 Inhibitors Utilizing Structure Guided Drug Design
Class: transferase
Keywords: Chk1, V158411, fragment, kinase, transferase
Deposited on 2015-09-07, released 2015-10-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-11-25, with a file datestamp of 2015-11-20.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase Chk1
    Species: Homo sapiens [TaxId:9606]
    Gene: CHEK1, CHK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5dlsa_
  • Heterogens: 5CV, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5dlsA (A:)
mavpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicink
mlnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvy
lhgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellk
rrefhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsapla
llhkilvenpsaritipdikkdrwynkplkkgakrprvtsggvsespsghhhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5dlsA (A:)
vedwdlvqtlgegaygevqlavnrvteeavavkivdmnikkeicinkmlnhenvvkfygh
rregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdikp
enlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvws
cgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsar
itipdikkdrwynkplk