PDB entry 5dkh

View 5dkh on RCSB PDB site
Description: Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with a hydroxyphenyl propenone inhibitor 17
Class: transcription
Keywords: SWI-SNF complex, chromatin remodeling, Brg associated factors (BAF), transcription
Deposited on 2015-09-03, released 2016-09-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-09-14, with a file datestamp of 2016-09-09.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable global transcription activator SNF2L2
    Species: Homo sapiens [TaxId:9606]
    Gene: SMARCA2, BAF190B, BRM, SNF2A, SNF2L2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5dkha_
  • Chain 'B':
    Compound: Probable global transcription activator SNF2L2
    Species: Homo sapiens [TaxId:9606]
    Gene: SMARCA2, BAF190B, BRM, SNF2A, SNF2L2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5dkhb_
  • Chain 'C':
    Compound: Probable global transcription activator SNF2L2
    Species: Homo sapiens [TaxId:9606]
    Gene: SMARCA2, BAF190B, BRM, SNF2A, SNF2L2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5dkhc_
  • Heterogens: ZN, 5C0, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5dkhA (A:)
smaeklspnppkltkqmnaiidtvinykdssgrqlsevfiqlpsrkelpeyyelirkpvd
fkkikerirnhkyrslgdlekdvmllchnaqtfnlegsqiyedsivlqsvfksarqkiak
eee

    Sequence, based on observed residues (ATOM records): (download) 
    >5dkhA (A:)
spnppkltkqmnaiidtvinykdssgrqlsevfiqlpsrkelpeyyelirkpvdfkkike
rirnhkyrslgdlekdvmllchnaqtfnlegsqiyedsivlqsvfksarqkiakee

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5dkhB (B:)
smaeklspnppkltkqmnaiidtvinykdssgrqlsevfiqlpsrkelpeyyelirkpvd
fkkikerirnhkyrslgdlekdvmllchnaqtfnlegsqiyedsivlqsvfksarqkiak
eee

    Sequence, based on observed residues (ATOM records): (download) 
    >5dkhB (B:)
pkltkqmnaiidtvinykdssgrqlsevfiqlpsrkelpeyyelirkpvdfkkikerirn
hkyrslgdlekdvmllchnaqtfnlegsqiyedsivlqsvfksarqkiak

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5dkhC (C:)
smaeklspnppkltkqmnaiidtvinykdssgrqlsevfiqlpsrkelpeyyelirkpvd
fkkikerirnhkyrslgdlekdvmllchnaqtfnlegsqiyedsivlqsvfksarqkiak
eee

    Sequence, based on observed residues (ATOM records): (download) 
    >5dkhC (C:)
ppkltkqmnaiidtvinykdssgrqlsevfiqlpsrkelpeyyelirkpvdfkkikerir
nhkyrslgdlekdvmllchnaqtfnlegsqiyedsivlqsvfksarqkiakee