PDB entry 5diu
View 5diu on RCSB PDB site
Description: The Fk1 domain of FKBP51 in complex with the new synthetic ligand 2-(3-((R)-1-((S)-1-((S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxamido)-3-(3,4-dimethoxyphenyl)propyl)phenoxy)acetic acid
Class: isomerase
Keywords: Fk-506 binding domain, Hsp90 cochaperone, immunophiline, peptidyl-prolyl isomerase, ligand selectivity, isomerase
Deposited on
2015-09-01, released
2016-03-23
The last revision prior to the SCOPe 2.06 freeze date was dated
2016-04-06, with a file datestamp of
2016-04-01.
No data on structure quality are available
Chains and heterogens:
- Chain 'A':
Compound: Peptidyl-prolyl cis-trans isomerase FKBP5
Species: Homo sapiens [TaxId:9606]
Gene: FKBP5, AIG6, FKBP51
Database cross-references and differences (RAF-indexed):
- Uniprot Q13451 (3-127)
- expression tag (0-2)
- engineered mutation (6)
Domains in SCOPe 2.06: d5diua_ - Heterogens: 5BG, HOH