PDB entry 5dhk

View 5dhk on RCSB PDB site
Description: Nicotiana tabacum 5-epi-aristolochene synthase mutant W273E - alkylated
Class: lyase
Keywords: sesquiterpene synthase, 5-epi-aristolochene synthase, farnesylation, active site alkylation, LYASE
Deposited on 2015-08-31, released 2015-09-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-20, with a file datestamp of 2017-09-15.
Experiment type: XRAY
Resolution: 2.43 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5-epi-aristolochene synthase
    Species: Nicotiana tabacum [TaxId:4097]
    Gene: EAS3, EAS4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q40577 (0-535)
      • engineered mutation (260)
    Domains in SCOPe 2.07: d5dhka1, d5dhka2
  • Heterogens: MG, FAR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5dhkA (A:)
    ivrpvadfspslwgdqflsfsiknqvaekyakeiealkeqtrnmllatgmkladtlnlid
    tierlgisyhfekeiddildqiynqnsncndlctsalqfrllrqhgfnispeifskfqde
    ngkfkeslasdvlgllnlyeashvrthaddiledalafstihlesaaphlksplreqvth
    aleqclhkgvprvetrffissiydkeqsknnvllrfakldfnllqmlhkqelaqvsrwwk
    dldfvttlpyardrvvecyfealgvyfepqysqarvmlvktismisivddtfdaygtvke
    leaytdaiqrwdineidrlpdymkisykaildlykdyekelssagrshivchaiermkev
    vrnynvestwfiegytppvseylsnalatttyyylattsylgmksateqdfewlsknpki
    leasviicrviddtatyeveksrgqiatgieccmrdygistkeamakfqnmaetawkdin
    egllrptpvstefltpilnlarivevtyihnldgythpekvlkphiinllvdsiki