PDB entry 5dg3

View 5dg3 on RCSB PDB site
Description: Structure of Pseudomonas aeruginosa LpxA in complex with UDP-3-O-(R-3-hydroxydecanoyl)-GlcNAc
Class: transferase
Keywords: Acyltransferases, Catalytic Domain, UDP-GlcNAc, Fatty Acids, Lipid A, Substrate Specificity, Uridine Diphosphate N-Acetylglucosamine, Hydrocarbon Rulers, TRANSFERASE
Deposited on 2015-08-27, released 2015-09-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa (strain PA7) [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5dg3a_
  • Chain 'B':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa (strain PA7) [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5dg3b_
  • Chain 'C':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa (strain PA7) [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5dg3c_
  • Chain 'D':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa (strain PA7) [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5dg3d_
  • Chain 'E':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa (strain PA7) [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5dg3e_
  • Chain 'F':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa (strain PA7) [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5dg3f_
  • Heterogens: U21, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5dg3A (A:)
    mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
    fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
    hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
    vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
    evavfrdsiqsatrgitr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5dg3A (A:)
    lidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqfs
    svgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahighd
    svignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayvt
    vfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpev
    avfrdsiqsatrgitr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5dg3B (B:)
    mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
    fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
    hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
    vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
    evavfrdsiqsatrgitr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5dg3B (B:)
    slidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqf
    ssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahigh
    dsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayv
    tvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpe
    vavfrdsiqsatrgitr
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >5dg3C (C:)
    mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
    fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
    hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
    vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
    evavfrdsiqsatrgitr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5dg3C (C:)
    lidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqfs
    svgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahighd
    svignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayvt
    vfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpev
    avfrdsiqsatrgitr
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >5dg3D (D:)
    mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
    fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
    hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
    vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
    evavfrdsiqsatrgitr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5dg3D (D:)
    lidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqfs
    svgedtpptrlvigdhnviregvtihrgtvqdraettigdhnlimayahighdsvignhc
    ilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayvtvfgnpae
    arsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpevavfrdsi
    qsatrgitr
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >5dg3E (E:)
    mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
    fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
    hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
    vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
    evavfrdsiqsatrgitr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5dg3E (E:)
    lidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqfs
    svgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahighd
    svignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayvt
    vfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpev
    avfrdsiqsatrgitr
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >5dg3F (F:)
    mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
    fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
    hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
    vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
    evavfrdsiqsatrgitr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5dg3F (F:)
    slidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqf
    ssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahigh
    dsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayv
    tvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpe
    vavfrdsiqsatrgitr