PDB entry 5de4

View 5de4 on RCSB PDB site
Description: Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-fluorophenyl-ACEPC
Class: transport protein, receptor
Keywords: NMDA receptor, Antagonist, TRANSPORT PROTEIN, RECEPTOR
Deposited on 2015-08-25, released 2016-09-14
Made obsolete by 5vih on 2017-06-21

The last revision prior to the SCOPe 2.06 freeze date was dated 2016-09-14, with a file datestamp of 2016-09-09.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor ionotropic, NMDA 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grin1, Nmdar1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35439 (Start-151)
      • linker (152-153)
    • Uniprot P35439 (154-End)
    Domains in SCOPe 2.06: d5de4a_
  • Chain 'B':
    Compound: Glutamate receptor ionotropic, NMDA 2A
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grin2a
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00959 (Start-138)
      • linker (139-140)
    • Uniprot Q00959 (141-End)
      • see remark 999 (238)
    Domains in SCOPe 2.06: d5de4b_
  • Heterogens: GLY, 5DZ, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5de4A (A:)
gmstrlkivtihqepfvyvkptmsdgtckeeftvngdpvkkvictgpndtspgsprhtvp
qccygfcidlliklartmnftyevhlvadgkfgtqervnnsnkkewngmmgellsgqadm
ivapltinneraqyiefskpfkyqgltilvkkgtritgindprlrnpsdkfiyatvkqss
vdiyfrrqvelstmyrhmekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlvt
tgelffrsgfgigmrkdspwkqnvslsilkshengfmedldktwvryqecds

    Sequence, based on observed residues (ATOM records): (download) 
    >5de4A (A:)
rlkivtihqepfvyvkptmsdgtckeeftvngdpvkkvictgptvpqccygfcidllikl
artmnftyevhlvadgkfgtqervnkkewngmmgellsgqadmivapltinneraqyief
skpfkyqgltilvkkgtritgindprlrnpsdkfiyatvkqssvdiyfrrqvelstmyrh
mekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlvttgelffrsgfgigmrkd
spwkqnvslsilkshengfmedldktwvr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5de4B (B:)
sddnhlsivtleeapfvivedidpltetcvrntvpcrkfvkinnstnegmnvkkcckgfc
idilkklsrtvkftydlylvtngkhgkkvnnvwngmigevvyqravmavgsltineerse
vvdfsvpfvetgisvmvsrgtqvtglsdkkfqrphdysppfrfgtvpngsternirnnyp
ymhqymtrfnqrgvedalvslktgkldafiydaavlnykagrdegcklvtigsgyifatt
gygialqkgspwkrqidlallqfvgdgemeeletlwltgichn

    Sequence, based on observed residues (ATOM records): (download) 
    >5de4B (B:)
dnhlsivtleeapfvivedidpltcvrntvpcrkfvkinnstnegmnvkkcckgfcidil
kklsrtvkftydlylvtngkhgkkvnnvwngmigevvyqravmavgsltineersevvdf
svpfvetgisvmvsrgtqvtglsdkkfqrphdysppfrfgtvpngsternirnnypymhq
ymtrfnqrgvedalvslktgkldafiydaavlnykagrdegcklvtigsgyifattgygi
alqkgspwkrqidlallqfvgdgemeeletlwltgich