PDB entry 5dde

View 5dde on RCSB PDB site
Description: Menin in complex with MI-859
Class: protein binding/inhibitor
Keywords: PROTEIN BINDING-INHIBITOR complex
Deposited on 2015-08-24, released 2015-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Menin
    Species: Homo sapiens [TaxId:9606]
    Gene: MEN1, SCG2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ddea1, d5ddea2, d5ddea3
  • Heterogens: 5A0, SO4, DMS, PG4, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ddeA (A:)
ggsssmglkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrvgl
tyfpvadlsiiaalyarftaqirgavdlslypreggvssrelvkkvsdviwnslsrsyfk
drahiqslfsfitgtkldssgvafavvgacqalglrdvhlalsedhawvvfgpngeqtae
vtwhgkgnedrrgqtvnagvaerswlylkgsymrcdrkmevafmvcainpsidlhtdsle
llqlqqkllwllydlghlerypmalgnladleeleptpgrpdpltlyhkgiasaktyyrd
ehiypymylagyhcrnrnvrealqawadtatviqdynycredeeiykeffevandvipnl
lkeaaslleagsqgsalqdpecfahllrfydgickweegsptpvlhvgwatflvqslgrf
egqvrqkvrivsvpapaaspppegpvltfqsekmkgmkellvatkinssaiklqltaqsq
vqmkkqkvs

    Sequence, based on observed residues (ATOM records): (download) 
    >5ddeA (A:)
glkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrvgltyfpva
dlsiiaalyarftaqirgavdlslypreggvssrelvkkvsdviwnslsrsyfkdrahiq
slfsfitgtkldssgvafavvgacqalglrdvhlalsedhawvvfgpngeqtaevtwhgk
gnedrrgqtvnagvaerswlylkgsymrcdrkmevafmvcainpsidlhtdslellqlqq
kllwllydlghlerypmalgnladleeleptpgrpdpltlyhkgiasaktyyrdehiypy
mylagyhcrnrnvrealqawadtatviqdynycredeeiykeffevandvipnllkeaas
lleagsqgsalqdpecfahllrfydgickweegsptpvlhvgwatflvqslgrfegqvrq
kvrivspvltfqsekmkgmkellvatkinssaiklqltaqsqvqmk