PDB entry 5d7n

View 5d7n on RCSB PDB site
Description: Crystal structure of human Sirt3 at an improved resolution
Class: Hydrolase
Keywords: Hydrolase, Sirtuin 3, Deacylase
Deposited on 2015-08-14, released 2015-12-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-12-09, with a file datestamp of 2015-12-04.
Experiment type: XRAY
Resolution: 1.83 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT3, SIR2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5d7na_
  • Chain 'B':
    Compound: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT3, SIR2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5d7nb_
  • Chain 'C':
    Compound: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT3, SIR2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5d7nc_
  • Chain 'D':
    Compound: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT3, SIR2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5d7nd_
  • Chain 'E':
    Compound: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT3, SIR2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5d7ne_
  • Chain 'F':
    Compound: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT3, SIR2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5d7nf_
  • Heterogens: ZN, PEG, MG, 1PE, GOL, PGE, PG4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5d7nA (A:)
ghmsdkgklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlp
ypeaifelpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidgle
rvsgipasklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivff
geplpqrfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawh
prsrdvaqlgdvvhgveslvellgwteemrdlvqretgkld

    Sequence, based on observed residues (ATOM records): (download) 
    >5d7nA (A:)
gklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlpypeaif
elpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidglervsgip
asklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffgeplpq
rfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhprsrdv
aqlgdvvhgveslvellgwteemrdlvqret

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5d7nB (B:)
ghmsdkgklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlp
ypeaifelpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidgle
rvsgipasklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivff
geplpqrfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawh
prsrdvaqlgdvvhgveslvellgwteemrdlvqretgkld

    Sequence, based on observed residues (ATOM records): (download) 
    >5d7nB (B:)
klslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlpypeaife
lpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidglervsgipa
sklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffgeplpqr
fllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhprsrdva
qlgdvvhgveslvellgwteemrdlvqretgk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5d7nC (C:)
ghmsdkgklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlp
ypeaifelpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidgle
rvsgipasklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivff
geplpqrfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawh
prsrdvaqlgdvvhgveslvellgwteemrdlvqretgkld

    Sequence, based on observed residues (ATOM records): (download) 
    >5d7nC (C:)
gklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlpypeaif
elpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidglervsgip
asklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffgeplpq
rfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhprsrdv
aqlgdvvhgveslvellgwteemrdlvqretg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5d7nD (D:)
ghmsdkgklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlp
ypeaifelpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidgle
rvsgipasklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivff
geplpqrfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawh
prsrdvaqlgdvvhgveslvellgwteemrdlvqretgkld

    Sequence, based on observed residues (ATOM records): (download) 
    >5d7nD (D:)
gklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlpypeaif
elpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidglervsgip
asklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffgeplpq
rfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhprsrdv
aqlgdvvhgveslvellgwteemrdlvqretg

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5d7nE (E:)
ghmsdkgklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlp
ypeaifelpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidgle
rvsgipasklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivff
geplpqrfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawh
prsrdvaqlgdvvhgveslvellgwteemrdlvqretgkld

    Sequence, based on observed residues (ATOM records): (download) 
    >5d7nE (E:)
klslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlpypeaife
lpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidglervsgipa
sklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffgeplpqr
fllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhprsrdva
qlgdvvhgveslvellgwteemrdlvqretg

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5d7nF (F:)
ghmsdkgklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlp
ypeaifelpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidgle
rvsgipasklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivff
geplpqrfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawh
prsrdvaqlgdvvhgveslvellgwteemrdlvqretgkld

    Sequence, based on observed residues (ATOM records): (download) 
    >5d7nF (F:)
klslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlpypeaife
lpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidglervsgipa
sklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffgeplpqr
fllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhprsrdva
qlgdvvhgveslvellgwteemrdlvqret