PDB entry 5d3n

View 5d3n on RCSB PDB site
Description: First bromodomain of BRD4 bound to inhibitor XD40
Class: transcription
Keywords: Gene regulation, Bromodomain, Inhibitor, transcription
Deposited on 2015-08-06, released 2016-01-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-09-06, with a file datestamp of 2017-09-01.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 4
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD4, HUNK1
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (0-125)
    • engineered mutation (0)
  Domains in SCOPe 2.08: d5d3na_
• Heterogens: L40, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5d3nA (A:)
  mnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiik
  tpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkin
  elptee