PDB entry 5cvd

View 5cvd on RCSB PDB site
Description: Crystal structure of human NRMT1 in complex with alpha-N-dimethylated human CENP-A peptide
Class: transferase/peptide
Keywords: Alpha-N-methyltransferase, Histone Methylation, SAM-MTase, CENP-A, TRANSFERASE-PEPTIDE complex
Deposited on 2015-07-26, released 2015-11-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-12-02, with a file datestamp of 2015-11-27.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: N/A
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N-terminal Xaa-Pro-Lys N-methyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NTMT1, NRMT1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BV86 (20-242)
      • expression tag (12-19)
    Domains in SCOPe 2.08: d5cvda1, d5cvda2
  • Chain 'B':
    Compound: N-terminal Xaa-Pro-Lys N-methyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NTMT1, NRMT1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BV86 (20-242)
      • expression tag (17-19)
    Domains in SCOPe 2.08: d5cvdb1, d5cvdb2
  • Chain 'D':
    Compound: N-teminal peptide from Histone H3-like centromeric protein A
    Species: Homo sapiens [TaxId:9606]
    Gene: CENPA
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: N-teminal peptide from Histone H3-like centromeric protein A
    Species: Homo sapiens [TaxId:9606]
    Gene: CENPA
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SAH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5cvdA (A:)
mgsshhhhhhssglvprgshmtseviedekqfyskaktywkqipptvdgmlggyghissi
dinssrkflqrflregpnktgtscaldcgagigritkrlllplfrevdmvditedflvqa
ktylgeegkrvrnyfccglqdftpepdsydviwiqwvighltdqhlaeflrrckgslrpn
giivikdnmaqegvilddvdssvcrdldvvrriicsaglsllaeerqenlpdeiyhvysf
alr

    Sequence, based on observed residues (ATOM records): (download) 
    >5cvdA (A:)
glvprgshmtseviedekqfyskaktywkqipptvdgmlggyghissidinssrkflqrf
lregpnktgtscaldcgagigritkrlllplfrevdmvditedflvqaktylgeegkrvr
nyfccglqdftpepdsydviwiqwvighltdqhlaeflrrckgslrpngiivikdnmaqe
gvilddvdssvcrdldvvrriicsaglsllaeerqenlpdeiyhvysfalr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5cvdB (B:)
mgsshhhhhhssglvprgshmtseviedekqfyskaktywkqipptvdgmlggyghissi
dinssrkflqrflregpnktgtscaldcgagigritkrlllplfrevdmvditedflvqa
ktylgeegkrvrnyfccglqdftpepdsydviwiqwvighltdqhlaeflrrckgslrpn
giivikdnmaqegvilddvdssvcrdldvvrriicsaglsllaeerqenlpdeiyhvysf
alr

    Sequence, based on observed residues (ATOM records): (download) 
    >5cvdB (B:)
gshmtseviedekqfyskaktywkqipptvdgmlggyghissidinssrkflqrflregp
nktgtscaldcgagigritkrlllplfrevdmvditedflvqaktylgeegkrvrnyfcc
glqdftpepdsydviwiqwvighltdqhlaeflrrckgslrpngiivikdnmaqegvild
dvdssvcrdldvvrriicsaglsllaeerqenlpdeiyhvysfalr

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.