PDB entry 5ctx

View 5ctx on RCSB PDB site
Description: Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
Class: isomerase/isomerase inhibitor
Keywords: DNA gyrase, GyrB, fragment-based screening, structure-based design, ISOMERASE-ISOMERASE INHIBITOR complex
Deposited on 2015-07-24, released 2016-02-03
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-02-17, with a file datestamp of 2016-02-12.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA gyrase subunit b
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: GYRB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5ctxa_
  • Chain 'B':
    Compound: DNA gyrase subunit b
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: GYRB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5ctxb_
  • Heterogens: MPD, 55G, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ctxA (A:)
gsvtalsdvnntdnygagqiqvlegleavrkrpgmyigstserglhhlvweivdnsidea
lagyanqievviekdnwikvtdngrgipvdiqekmgrpaveviltssvvnalsqdlevyv
hrnetiyhqaykkgvpqfdlkevgttdktgtvirfkadgeiftettvynyetlqqrirel
aflnkgiqitlrderdeenvredsyhyeggik

    Sequence, based on observed residues (ATOM records): (download) 
    >5ctxA (A:)
agqiqvlegleavrkrpgmyigstserglhhlvweivdnsidealagyanqievviekdn
wikvtdngrgipvdiqekmgrpaveviltssvvnalsqdlevyvhrnetiyhqaykkgvp
qfdlkevgttdktgtvirfkadgeiftettvynyetlqqrirelaflnkgiqitlrderd
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  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ctxB (B:)
gsvtalsdvnntdnygagqiqvlegleavrkrpgmyigstserglhhlvweivdnsidea
lagyanqievviekdnwikvtdngrgipvdiqekmgrpaveviltssvvnalsqdlevyv
hrnetiyhqaykkgvpqfdlkevgttdktgtvirfkadgeiftettvynyetlqqrirel
aflnkgiqitlrderdeenvredsyhyeggik

    Sequence, based on observed residues (ATOM records): (download) 
    >5ctxB (B:)
qvlegleavrkrpgmyigstserglhhlvweivdnsidealagyanqievviekdnwikv
tdngrgipvdiqekmgrpaveviltssvvnalsqdlevyvhrnetiyhqaykkgvpqfdl
kevgttdktgtvirfkadgeiftettvynyetlqqrirelaflnkgiqitlrderdeenv
redsyhyeg