PDB entry 5ct2
View 5ct2 on RCSB PDB site
Description: The structure of the NK1 fragment of HGF/SF complexed with CAPS
Class: hormone
Keywords: HGF/SF, NK1 fragment, fragment based drug discovery, growth factor, cell cycle, hormone, new chemical entity
Deposited on
2015-07-23, released
2015-08-12
The last revision prior to the SCOPe 2.07 freeze date was dated
2016-10-26, with a file datestamp of
2016-10-21.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hepatocyte growth factor
Species: Homo sapiens [TaxId:9606]
Gene: HGF, HPTA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d5ct2a1, d5ct2a2 - Chain 'B':
Compound: hepatocyte growth factor
Species: Homo sapiens [TaxId:9606]
Gene: HGF, HPTA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d5ct2b1, d5ct2b2 - Heterogens: CXS, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5ct2A (A:)
yvegqrkrrntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckaf
vfdkarkqclwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgi
kcqpwssmiphehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcs
eve
Sequence, based on observed residues (ATOM records): (download)
>5ct2A (A:)
tihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckafvfdkarkqcl
wfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgikcqpwssmip
hehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcseve
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5ct2B (B:)
yvegqrkrrntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckaf
vfdkarkqclwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgi
kcqpwssmiphehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcs
eve
Sequence, based on observed residues (ATOM records): (download)
>5ct2B (B:)
ntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckafvfdkarkqc
lwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgikcqpwssmi
phehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcsev