PDB entry 5cs9
View 5cs9 on RCSB PDB site
Description: The structure of the NK1 fragment of HGF/SF complexed with MES
Class: hormone
Keywords: HGF/SF, NK1 fragment, fragment based drug discovery, growth factor, cell cycle, hormone, new chemical entity
Deposited on
2015-07-23, released
2015-08-12
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-08-29, with a file datestamp of
2018-08-24.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hepatocyte growth factor
Species: Homo sapiens [TaxId:9606]
Gene: HGF, HPTA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5cs9a1, d5cs9a2 - Chain 'B':
Compound: hepatocyte growth factor
Species: Homo sapiens [TaxId:9606]
Gene: HGF, HPTA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5cs9b1, d5cs9b2 - Heterogens: MES, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5cs9A (A:)
yvegqrkrrntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckaf
vfdkarkqclwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgi
kcqpwssmiphehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcs
eve
Sequence, based on observed residues (ATOM records): (download)
>5cs9A (A:)
tihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckafvfdkarkqcl
wfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgikcqpwssmip
hehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcsev
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5cs9B (B:)
yvegqrkrrntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckaf
vfdkarkqclwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgi
kcqpwssmiphehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcs
eve
Sequence, based on observed residues (ATOM records): (download)
>5cs9B (B:)
rntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckafvfdkarkq
clwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgikcqpwssm
iphehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcsev