PDB entry 5coe

View 5coe on RCSB PDB site
Description: The structure of the NK1 fragment of HGF/SF complexed with HEPES
Class: hormone
Keywords: HGF/SF, fragment based discovery, growth factor, NK1 fragment, cell cycle, hormone
Deposited on 2015-07-20, released 2015-08-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-08-29, with a file datestamp of 2018-08-24.
Experiment type: XRAY
Resolution: 2.18 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hepatocyte growth factor
    Species: Homo sapiens [TaxId:9606]
    Gene: HGF, HPTA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5coea1, d5coea2
  • Chain 'B':
    Compound: hepatocyte growth factor
    Species: Homo sapiens [TaxId:9606]
    Gene: HGF, HPTA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5coeb1, d5coeb2
  • Heterogens: EPE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5coeA (A:)
    yvegqrkrrntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckaf
    vfdkarkqclwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgi
    kcqpwssmiphehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcs
    eve
    

    Sequence, based on observed residues (ATOM records): (download)
    >5coeA (A:)
    tihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckafvfdkarkqcl
    wfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgikcqpwssmip
    hehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcseve
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5coeB (B:)
    yvegqrkrrntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckaf
    vfdkarkqclwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgi
    kcqpwssmiphehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcs
    eve
    

    Sequence, based on observed residues (ATOM records): (download)
    >5coeB (B:)
    ntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckafvfdkarkqc
    lwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgikcqpwssmi
    phehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcsev