PDB entry 5cm4

View 5cm4 on RCSB PDB site
Description: Crystal structure of human Frizzled 4 Cysteine-Rich Domain (CRD)
Class: signaling protein
Keywords: Wnt signaling, Norrin signaling, Frizzled 4 extracelluar domain, Cysteine-Rich Domain, SIGNALING PROTEIN
Deposited on 2015-07-16, released 2015-08-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Frizzled-4
    Species: Homo sapiens [TaxId:9606]
    Gene: FZD4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5cm4a_
  • Chain 'B':
    Compound: Frizzled-4
    Species: Homo sapiens [TaxId:9606]
    Gene: FZD4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5cm4b_
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5cm4A (A:)
    eeerrcdpirismcqnlgynvtkmpnlvghelqtdaelqlttftpliqygcssqlqfflc
    svyvpmctekinipigpcggmclsvkrrcepvlkefgfawpeslncskfppqndhnhmcm
    egpgd
    

    Sequence, based on observed residues (ATOM records): (download)
    >5cm4A (A:)
    rcdpirismcqnlgynvtkmpnlvghelqtdaelqlttftpliqygcssqlqfflcsvyv
    pmctekinipigpcggmclsvkrrcepvlkefgfawpeslncskfppqndhnhmcmegpg
    d
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5cm4B (B:)
    eeerrcdpirismcqnlgynvtkmpnlvghelqtdaelqlttftpliqygcssqlqfflc
    svyvpmctekinipigpcggmclsvkrrcepvlkefgfawpeslncskfppqndhnhmcm
    egpgd
    

    Sequence, based on observed residues (ATOM records): (download)
    >5cm4B (B:)
    rcdpirismcqnlgynvtkmpnlvghelqtdaelqlttftpliqygcssqlqfflcsvyv
    pmctekinipigpcggmclsvkrrcepvlkefgfawpeslncskfppqndhnhmcmegpg
    d