PDB entry 5cah

View 5cah on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 6H-thieno[2,3-b]pyrrole-5-carboxylic acid
Class: transferase
Keywords: Fragment, Complex, TRANSFERASE
Deposited on 2015-06-29, released 2016-08-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: malate synthase g
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: glcB, Rv1837c, MTCY1A11.06
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WK17
      • engineered mutation (618)
    Domains in SCOPe 2.07: d5caha_
  • Heterogens: MG, 4ZA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5cahA (A:)
    mtdrvsvgnlriarvlydfvnnealpgtdidpdsfwagvdkvvadltpqnqallnardel
    qaqidkwhrrrviepidmdayrqflteigyllpepddftittsgvdaeitttagpqlvvp
    vlnarfalnaanarwgslydalygtdvipetdgaekgptynkvrgdkviayarkflddsv
    plssgsfgdatgftvqdgqlvvalpdkstglanpgqfagytgaaesptsvllinhglhie
    ilidpesqvgttdragvkdvilesaittimdfedsvaavdaadkvlgyrnwlglnkgdla
    aavdkdgtaflrvlnrdrnytapgggqftlpgrslmfvrnvghlmtndaivdtdgsevfe
    gimdalftgliaihglkasdvngplinsrtgsiyivkpkmhgpaevaftcelfsrvedvl
    glpqntmkigimdeerrttvnlkacikaaadrvvfintgfldrtgdeihtsmeagpmvrk
    gtmksqpwilayedhnvdaglaagfsgraqvgkgmwtmtelmadmvetkiaqpragasta
    wvpsptaatlhalhyhqvdvaavqqglagkrratieqlltiplakelawapdeireevdn
    ncqsilgyvvrwvdqgvgaskvpdihdvalmedratlrissqllanwlrhgvitsadvra
    slermaplvdrqnagdvayrpmapnfddsiaflaaqelilsgaqqpngytepilhrrrre
    fkaraaekpapsdragddaar
    

    Sequence, based on observed residues (ATOM records): (download)
    >5cahA (A:)
    tdrvsvgnlriarvlydfvnnealpgtdidpdsfwagvdkvvadltpqnqallnardelq
    aqidkwhrrridmdayrqflteigyllpepddftittsgvdaeitttagpqlvvpvlnar
    falnaanarwgslydalygtdvipetdgaekgptynkvrgdkviayarkflddsvplssg
    sfgdatgftvqdgqlvvalpdkstglanpgqfagytgaaesptsvllinhglhieilidp
    esqvgttdragvkdvilesaittimdfedsvaavdaadkvlgyrnwlglnkgdlaarvln
    rdrnytapgggqftlpgrslmfvrnvghlmtndaivdtdgsevfegimdalftgliaihg
    lkalinsrtgsiyivkpkmhgpaevaftcelfsrvedvlglpqntmkigimdeerrttvn
    lkacikaaadrvvfintgfldrtgdeihtsmeagpmvrkgtmksqpwilayedhnvdagl
    aagfsgraqvgkgmwtmtelmadmvetkiaqpragastawvpsptaatlhalhyhqvdva
    avqqglagkrratieqlltiplakelawapdeireevdnncqsilgyvvrwvdqgvgask
    vpdihdvalmedratlrissqllanwlrhgvitsadvraslermaplvdrqnagdvayrp
    mapnfddsiaflaaqelilsgaqqpngytepilhrrrrefkaraae