PDB entry 5c6w

View 5c6w on RCSB PDB site
Description: anti-CXCL13 scFv - E10
Class: immune system
Keywords: anti-CXCL13, scFv, IMMUNE SYSTEM
Deposited on 2015-06-23, released 2015-11-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.54 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Protein IGHV1-69-2,Ig lambda chain V-II region NIG-84
    Species: Homo sapiens [TaxId:9606]
    Gene: IGHV1-69-2
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0B4J2H0 (0-97)
      • linker (98-126)
    • Uniprot P04209 (142-End)
      • conflict (153)
      • conflict (167)
      • conflict (172)
      • conflict (175)
      • conflict (192)
      • conflict (196)
      • conflict (201)
      • conflict (203)
      • conflict (232)
      • conflict (234)
      • conflict (236-240)
      • conflict (244)
      • conflict (248-249)
    Domains in SCOPe 2.08: d5c6wh1, d5c6wh2
  • Chain 'J':
    Compound: Protein IGHV1-69-2,Ig lambda chain V-II region NIG-84
    Species: Homo sapiens [TaxId:9606]
    Gene: IGHV1-69-2
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0B4J2H0 (0-97)
      • linker (98-126)
    • Uniprot P04209 (142-252)
      • conflict (153)
      • conflict (167)
      • conflict (172)
      • conflict (175)
      • conflict (192)
      • conflict (196)
      • conflict (201)
      • conflict (203)
      • conflict (232)
      • conflict (234)
      • conflict (236-240)
      • conflict (244)
      • conflict (248-249)
    Domains in SCOPe 2.08: d5c6wj1, d5c6wj2
  • Heterogens: CL, SO4, EDO, PEG, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5c6wH (H:)
qvqlvqsgaevkkpgssvkvsckasggtfssyaiswvrqapgqglewmggiipifgtany
aqkfqgrvtitadeststaymelsslrsedtavyycarepdyydssgyypidafdiwgqg
ttvtvssggggsggggsggggsqsaltqpasvsaspgqsitisctgtssdvgaydwvswy
qqhpgkapkllifdvnnrpsgvshrfsgsksgntasltisglqaedeadyycasatlldt
yvfgtgtkvtvlgdqepkssdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >5c6wH (H:)
qvqlvqsgaevkkpgssvkvsckasggtfssyaiswvrqapgqglewmggiipifgtany
aqkfqgrvtitadeststaymelsslrsedtavyycarepdyydssgyypidafdiwgqg
ttvtvssqsaltqpasvsaspgqsitisctgtssdvgaydwvswyqqhpgkapkllifdv
nnrpsgvshrfsgsksgntasltisglqaedeadyycasatlldtyvfgtgtkvtvl

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >5c6wJ (J:)
qvqlvqsgaevkkpgssvkvsckasggtfssyaiswvrqapgqglewmggiipifgtany
aqkfqgrvtitadeststaymelsslrsedtavyycarepdyydssgyypidafdiwgqg
ttvtvssggggsggggsggggsqsaltqpasvsaspgqsitisctgtssdvgaydwvswy
qqhpgkapkllifdvnnrpsgvshrfsgsksgntasltisglqaedeadyycasatlldt
yvfgtgtkvtvlgdqepkssdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >5c6wJ (J:)
qvqlvqsgaevkkpgssvkvsckasggtfssyaiswvrqapgqglewmggiipifgtany
aqkfqgrvtitadeststaymelsslrsedtavyycarepdyydssgyypidafdiwgqg
ttvtvssqsaltqpasvsaspgqsitisctgtssdvgaydwvswyqqhpgkapkllifdv
nnrpsgvshrfsgsksgntasltisglqaedeadyycasatlldtyvfgtgtkvtvlg