PDB entry 5c2j
View 5c2j on RCSB PDB site
Description: Complex structure of the GAP domain of MgcRacGAP and Cdc42
Class: hydrolase activator/signaling protein
Keywords: GTPase activation, Complex, small G-protein, HYDROLASE ACTIVATOR-SIGNALING PROTEIN complex
Deposited on
2015-06-16, released
2016-06-22
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-02-19, with a file datestamp of
2020-02-14.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Rac GTPase-activating protein 1
Species: Homo sapiens [TaxId:9606]
Gene: RACGAP1, KIAA1478, MGCRACGAP
Database cross-references and differences (RAF-indexed):
- Uniprot Q9H0H5 (7-207)
- see sequence details (179)
Domains in SCOPe 2.08: d5c2ja_ - Chain 'B':
Compound: Cell division control protein 42 homolog
Species: Mus musculus [TaxId:10090]
Gene: CDC42
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5c2jb_ - Heterogens: MG, GDP, AF3, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5c2jA (A:)
gssgssgigegmladfvsqtspmipsivvhcvneieqrgltetglyrisgcdrtvkelke
kflrvktvpllskvddihaicsllkdflrnlkeplltfrlnrafmeaaeitdednsiaam
yqavgelpqanrdtlaflmihlqrvaqsphtkmdvanlakvfgptivahavpnpdpvtms
qdikrqpkvverllslpleywsqfmmve
Sequence, based on observed residues (ATOM records): (download)
>5c2jA (A:)
igegmladfvsqtspmipsivvhcvneieqrgltetglyrisgcdrtvkelkekflrvkt
vpllskvddihaicsllkdflrnlkeplltfrlnrafmeaaeitdednsiaamyqavgel
pqanrdtlaflmihlqrvaqsphtkmdvanlakvfgptivahavpnpdpvtmsqdikrqp
kvverllslpleywsqfmmve
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5c2jB (B:)
gssgssgmqtikcvvvgdgavgktcllisyttnkfpseyvptvfdnyavtvmiggepytl
glfdtagqedydrlrplsypqtdvflvcfsvvspssfenvkekwvpeithhcpktpfllv
gtqidlrddpstieklaknkqkpitpetaeklardlkavkyvecsaltqkglknvfdeai
laaleppepkksrrcvll
Sequence, based on observed residues (ATOM records): (download)
>5c2jB (B:)
mqtikcvvvgdgavgktcllisyttnkfpseyvptvfdnyavtvmiggepytlglfdtag
qedydrlrplsypqtdvflvcfsvvspssfenvkekwvpeithhcpktpfllvgtqidlr
ddpstieklaknkqkpitpetaeklardlkavkyvecsaltqkglknvfdeailaalepp
epkksrrcvll