PDB entry 5c1u

View 5c1u on RCSB PDB site
Description: Crystal structure of EV71 3C Proteinase in complex with Compound Xb
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase, cysteine proteinase, inhibitor, hydrolase-hydrolase inhibitor complex
Deposited on 2015-06-15, released 2016-06-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C proteinase
    Species: Enterovirus A71 [TaxId:39054]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9XG43 (1-End)
      • expression tag (0)
    Domains in SCOPe 2.08: d5c1ua1, d5c1ua2
  • Chain 'B':
    Compound: 3C proteinase
    Species: Enterovirus A71 [TaxId:39054]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A9XG43 (1-End)
      • expression tag (0)
    Domains in SCOPe 2.08: d5c1ub1, d5c1ub2
  • Heterogens: GHV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5c1uA (A:)
mgpsldfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnilda
velvdeqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpvgdv
vqygflnlsgkpthrtmmynfptkagqcggvvtsvgkvigihiggngrqgfcaglkrsyf
aseqlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5c1uA (A:)
mgpsldfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnilda
velvdeqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpvgdv
vqygflnlsgkpthrtmmynfptkagqcggvvtsvgkvigihiggngrqgfcaglkrsyf
a

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5c1uB (B:)
mgpsldfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnilda
velvdeqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpvgdv
vqygflnlsgkpthrtmmynfptkagqcggvvtsvgkvigihiggngrqgfcaglkrsyf
aseqlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5c1uB (B:)
mgpsldfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnilda
velvdeqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpvgdv
vqygflnlsgkpthrtmmynfptkagqcggvvtsvgkvigihiggngrqgfcaglkrsyf
a