PDB entry 5bvd

View 5bvd on RCSB PDB site
Description: Tetrahydropyrrolo-diazepenones as inhibitors of ERK2 kinase
Class: TRANSFERASE/TRANSFERASE Inhibitor
Keywords: Inhibitor, Kinase, TRANSFERASE-TRANSFERASE Inhibitor complex
Deposited on 2015-06-05, released 2015-09-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-09-09, with a file datestamp of 2015-09-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK1, ERK2, PRKM1, PRKM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5bvda_
  • Heterogens: 4VF, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5bvdA (A:)
gpaaaaaagagpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispf
ehqtycqrtlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktq
hlsndhicyflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhd
htgflteyvatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnh
ilgilgspsqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnph
krieveqalahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgyr
s

    Sequence, based on observed residues (ATOM records): (download) 
    >5bvdA (A:)
agpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrt
lreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicy
flyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvtrwyrapeimlntks
idiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlkarnyllslp
hknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydpsdepiaeap
fkfdmelddlpkeklkelifeetarfqpgy