PDB entry 5bs4

View 5bs4 on RCSB PDB site
Description: HIV-1 wild Type protease with GRL-047-11A (a methylamine bis-Tetrahydrofuran P2-Ligand, 4-amino sulfonamide derivative)
Class: HYDROLASE/HYDROLASE Inhibitor
Keywords: HYDROLASE-HYDROLASE Inhibitor complex
Deposited on 2015-06-01, released 2015-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: XRAY
Resolution: 1.29 Å
R-factor: N/A
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Protease
  Species: Human immunodeficiency virus type 1 BH10 [TaxId:11678]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03366 (0-98)
    • engineered mutation (6)
    • engineered mutation (32)
    • engineered mutation (62)
    • engineered mutation (66)
    • engineered mutation (94)
  Domains in SCOPe 2.08: d5bs4a_
• Chain 'B':
  Compound: Protease
  Species: Human immunodeficiency virus type 1 BH10 [TaxId:11678]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03366 (0-98)
    • engineered mutation (6)
    • engineered mutation (32)
    • engineered mutation (62)
    • engineered mutation (66)
    • engineered mutation (94)
  Domains in SCOPe 2.08: d5bs4b_
• Heterogens: 4UX, NA, CL, ACT, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5bs4A (A:)
  pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5bs4B (B:)
  pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf