PDB entry 5brw

View 5brw on RCSB PDB site
Description: Catalytic Improvement of an Artificial Metalloenzyme by Computational Design
Class: oxidoreductase
Keywords: artificial metalloenzyme, lyase, imine reductase, transfer hydrogenase, oxidoreductase
Deposited on 2015-06-01, released 2015-06-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-08-26, with a file datestamp of 2015-08-21.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00918 (Start-259)
      • engineered mutation (139)
      • engineered mutation (196)
      • engineered mutation (204)
      • conflict (251)
    Domains in SCOPe 2.08: d5brwa_
  • Heterogens: ZN, SO4, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5brwA (A:)
mahhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslril
nnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhl
vhwntkygdfgkavqqpdgmavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdp
rgllpesldywtypgsmttppllesvtwivlkepisvsseqvlkfrklnfngegepeelm
vdnwrpaqplklrqikasfk

    Sequence, based on observed residues (ATOM records): (download) 
    >5brwA (A:)
hhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnn
ghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvh
wntkygdfgkavqqpdgmavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprg
llpesldywtypgsmttppllesvtwivlkepisvsseqvlkfrklnfngegepeelmvd
nwrpaqplklrqikasfk