PDB entry 5b32

View 5b32 on RCSB PDB site
Description: The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.3.
Class: DNA binding protein
Keywords: Histone variant, nucleosome, protein-DNA complex, DNA BINDING PROTEIN
Deposited on 2016-02-08, released 2016-08-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone H3.3
    Species: Homo sapiens [TaxId:9606]
    Gene: H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5b32a_
  • Chain 'B':
    Compound: histone h4
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5b32b_
  • Chain 'C':
    Compound: Histone H2A type 1-B/E
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H2AB, H2AFM, HIST1H2AE, H2AFA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5b32c_
  • Chain 'D':
    Compound: Histone H2B type 1-J
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H2BJ, H2BFR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5b32d_
  • Chain 'E':
    Compound: Histone H3.3
    Species: Homo sapiens [TaxId:9606]
    Gene: H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5b32e_
  • Chain 'F':
    Compound: histone h4
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5b32f_
  • Chain 'G':
    Compound: histone h2a.z
    Species: Homo sapiens [TaxId:9606]
    Gene: H2AFZ, H2AZ
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5b32g_
  • Chain 'H':
    Compound: Histone H2B type 1-J
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H2BJ, H2BFR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5b32h_
  • Chain 'I':
    Compound: DNA (146-mer)
    Species: Homo sapiens [TaxId:9606]
  • Chain 'J':
    Compound: DNA (146-mer)
    Species: Homo sapiens [TaxId:9606]
  • Heterogens: CL, MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5b32A (A:)
gshmartkqtarkstggkaprkqlatkaarksapstggvkkphryrpgtvalreirryqk
stellirklpfqrlvreiaqdfktdlrfqsaaigalqeaseaylvglfedtnlcaihakr
vtimpkdiqlarrirgera

    Sequence, based on observed residues (ATOM records): (download) 
    >5b32A (A:)
phryrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqsaaigalqease
aylvglfedtnlcaihakrvtimpkdiqlarrirger

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5b32B (B:)
gshmsgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrg
vlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records): (download) 
    >5b32B (B:)
niqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtam
dvvyalkrqgrtlygfgg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5b32C (C:)
gshmsgrgkqggkarakaktrssraglqfpvgrvhrllrkgnyservgagapvylaavle
yltaeilelagnaardnkktriiprhlqlairndeelnkllgrvtiaqggvlpniqavll
pkkteshhkakgk

    Sequence, based on observed residues (ATOM records): (download) 
    >5b32C (C:)
rakaktrssraglqfpvgrvhrllrkgnyservgagapvylaavleyltaeilelagnaa
rdnkktriiprhlqlairndeelnkllgrvtiaqggvlpniqavllpk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5b32D (D:)
gshmpepaksapapkkgskkavtkaqkkdgkkrkrsrkesysiyvykvlkqvhpdtgiss
kamgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtk
avtkytsak

    Sequence, based on observed residues (ATOM records): (download) 
    >5b32D (D:)
srkesysiyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstits
reiqtavrlllpgelakhavsegtkavtkytsa

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5b32E (E:)
gshmartkqtarkstggkaprkqlatkaarksapstggvkkphryrpgtvalreirryqk
stellirklpfqrlvreiaqdfktdlrfqsaaigalqeaseaylvglfedtnlcaihakr
vtimpkdiqlarrirgera

    Sequence, based on observed residues (ATOM records): (download) 
    >5b32E (E:)
phryrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqsaaigalqease
aylvglfedtnlcaihakrvtimpkdiqlarrirgera

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5b32F (F:)
gshmsgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrg
vlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records): (download) 
    >5b32F (F:)
rkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakr
ktvtamdvvyalkrqgrtlygfg

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5b32G (G:)
gshmaggkagkdsgkaktkavsrsqraglqfpvgrihrhlksrttshgrvgataavysaa
ileyltaevlelagnaskdlkvkritprhlqlairgdeeldslikatiagggviphihks
ligkkgqqktv

    Sequence, based on observed residues (ATOM records): (download) 
    >5b32G (G:)
avsrsqraglqfpvgrihrhlksrttshgrvgataavysaaileyltaevlelagnaskd
lkvkritprhlqlairgdeeldslikatiagggviphihkslig

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5b32H (H:)
gshmpepaksapapkkgskkavtkaqkkdgkkrkrsrkesysiyvykvlkqvhpdtgiss
kamgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtk
avtkytsak

    Sequence, based on observed residues (ATOM records): (download) 
    >5b32H (H:)
kesysiyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsre
iqtavrlllpgelakhavsegtkavtkytsa

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.